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020			_a9781071611074
024	7		_a10.1007/978-1-0716-1107-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP562 .G5 _b2021 EB
245	0	0	_aMetabotropic Glutamate Receptor Technologies : _cedited by M. Foster Olive, Brian T. Burrows, Jonna M. Leyrer-Jackson
250			_a1st edition 2021
264		1	_aNew York, NY _bSpringer International Publising _c2021
300			_a1 recurso en línea (XII, 314 páginas) _b71 ilustraciones, 60 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v164
505	0		_aTechnologies for Screening of mGlu Receptor Allosteric Modulators -- Positron Emission Tomography (PET) Imaging of Metabotropic Glutamate Receptor Subtype 2 (mGlu2) Based on a Negative Allosteric Modulator Radioligand -- PET Imaging of Type 5 Metabotropic Glutamate Receptors -- Electrophysiological and Calcium Imaging Approaches to Study Metabotropic Glutamate Receptors -- Role of Metabotropic Glutamate Receptors (mGluRs) in the Regulation of Intracellular Calcium Signaling: Theory, Protocols, and Data Analysis -- Optical Approaches for Modulating mGlu Receptor Activity -- Classic and Modern Approaches to Investigating Interactions between Dopamine Systems and Metabotropic Glutamate Receptors -- Using Western Blotting for the Evaluation of Metabotropic Glutamate Receptors within the Nervous System: Procedures and Technical Considerations -- Investigation of mGlu Receptor Cell Surface Trafficking in Acute Brain Slices Using Biotinylation -- Co-Labeling of Neuronal Cells using DiI Neuronal Filling and Immunohistochemistry to Explore Metabotropic Glutamate Receptor Expression -- Fluorescence Immunohistochemistry Techniques for Labelling Metabotropic Glutamate Receptors in the Central Nervous System -- Multiplex Arrays for Quantifying Relative Levels of Cytokines in Brain Tissue Lysates: Implications for mGlu Receptor Mediated Alterations -- mGlu Receptor Modulation in Murine Models of Stress and Affective Disorders -- Role of Metabotropic Glutamate Receptors in Alcohol Drinking Behaviors.
520			_aThis volume highlights various techniques used to study multiple aspects of mGlu receptor function. Chapters in this book cover topics such as modern approaches for the development and screening of allosteric modulators; fluctuations in intracellular calcium induced by mGlu receptor activation; dopamine-glutamate interactions in the central nervous system; methods for assessing mGlu receptor localization; and common techniques for evaluating mGlu modulation in behavior in rodents, including stress and alcohol drinking. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Metabotropic Glutamate Receptor Technologies provides researchers with a starting point to address important questions regarding mGlu and its importance. Researchers working in the fields of neuroscience and physiology of multiple peripheral systems will find this volume most useful. .
988			_aSpringer_Protocols_2021
650		7	_2embne _9155047 _aÁcido glutámico _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781071611067
776	0	8	_iPrinted edition: _z9781071611081
776	0	8	_iPrinted edition: _z9781071611098
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1107-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b08/2023 _dz _eu _zSI