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007			cr nn 008mamaa
008			100301s1997 xxu| o |||| 0|eng d
020			_a9781592596348
024	7		_a10.1385/0896034518 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH671 _b1997 EB
245	0	0	_aApoptosis Techniques and Protocols _cedited by Judes Poirier
250			_a1st edition 1997
264		1	_aTotowa, NJ _bHumana Press _c1997
300			_a1 recurso en línea (XI, 286 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v29
505	0		_aGene Tools to Study Neuronal Apoptosis -- Detection of Apoptotic or Necrotic Death in Neuronal Cells by Morphological, Biochemical, and Molecular Analysis -- Detection of Cell Death in Neural Tissue and Cell Culture -- Cultured Cerebellar Granule Neurons as a Model of Neuronal Apoptosis -- Optimization and Validation of RT-PCR as a Tool to Analyze Gene Expression During Apoptosis -- p53 Induction Is a Marker of Neuronal Apoptosis in the Central Nervous System -- Apoptosis and Ischemia in the Central Nervous System -- Analyses of Apoptosis- Associated DNA Fragmentation In Vivo During Neurodegeneration of the Peripheral Olfactory System in Adult Mammals -- Both Irreversible Neuronal Death and Reversible Neuronal Stress Are Associated with Increased Levels of Statin, a Marker of Cell Cycle Arrest -- ?-Amyloid-Induced Neuronal Cell Death in Transgenic Mice and Alzheimer's Disease -- Use of TUNEL to Measure Retinal Ganglion Cell Apoptosis -- Methods for Detection of Apoptosis in the CNS -- Techniques for Distinguishing Apoptosis from Necrosis in Cerebrocortical and Cerebellar Neurons -- The Nematode Caenorhabditis elegans as a Model System to Study Neuronal Cell Death.
520			_aIn Apoptosis Techniques and Protocols leading experts offer investigators at all levels of experience an indispensable introduction to the basics of apoptosis, as well as essential details of the methods used in its study. These authorities cover such important topics as the histological, biological, and molecular criteria for apoptosis and programmed cell death; necrosis and apoptosis in the CNS; and cellular, invertebrate, animal, and human models of apoptosis in Alzheimer's disease, AIDS, and stroke. The techniques they describe examine the critical steps involved in the apoptotic process, and include PCR analysis of cell-cycle-regulated proteins, histochemical analysis of DNA regulation, DNA laddering analysis, and cytochemical alterations of living cells. Apoptosis Techniques and Protocols provides a wide variety of significant methods for both experimental and clinical investigation. It is certain to serve as an illuminating introduction to the basic ideas behind the phenomena of apoptosis and necrosis, as well as a key technical reference on the significant methodologies used in the field.
988			_aSpringer_Protocols_1997
650		7	_2embne _9157983 _aApoptosis
776	0	8	_iPrinted edition: _z9781489939050
776	0	8	_iPrinted edition: _z9780896034518
776	0	8	_iPrinted edition: _z9781489939043
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/0896034518 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b05/2023 _dz _eIG _zSI