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020 _a9781071608647
024 7 _a10.1007/978-1-0716-0864-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP171
_b2021 EB
245 0 0 _aMetabolomics
_cedited by Paul L. Wood
250 _a1st edition 2021
264 1 _aNew York, NY
_bSpringer International Publising
_c2021
300 _a1 recurso en línea (XIII, 307 páginas)
_b53 ilustraciones, 41 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v159
505 0 _aFlow Infusion ESI High Resolution Mass Spectrometry Metabolomics Analytical Platforms -- High Throughput Metabolomics using Flow Injection Analysis and Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry -- Two-Dimensional Liquid Chromatography in Metabolomics and Lipidomics -- Metabolomics of Small Numbers of Cells using Chemical Isotope Labeling Combined with Nanoflow LC-MS -- Untargeted Metabolomics to Interpret the Effects of Social Defeat: Integrating Chemistry and Behavioral Approaches in Neuroscience -- Flow Infusion Electrospray Ionization High Resolution Mass Spectrometry of the Chloride Adducts of Sphingolipids, Glycerophospholipids, Glycerols, Hydroxy Fatty Acids, Fatty Acid Esters of Hydroxy Fatty Acids (FAHFA), and Modified Nucleosides -- High Mass Accuracy Gas Chromatography/Mass Spectrometry for Performing Isotopic Ratio Outlier Analysis: Applications for Non-Annotated Metabolite Detection -- Enantioseparation and Detection of (R)-2-hydroxyglutarate and (S)-2-hydroxyglutarate by Chiral Gas Chromatography-Triple Quadrupole Mass Spectrometry -- Enantioselective Supercritical Fluid Chromatography (SFC) for Chiral Metabolomics -- Capillary Electrophoresis-Mass Spectrometry of Hydrophilic Metabolomics -- Lipidomic Analysis of Oxygenated Polyunsaturated Fatty Acid-Derived-Inflammatory Mediators in Neurodegenerative Diseases -- The Characterization and Quantification of the Fatty Acid Amidome -- Metabolomics Analysis of Complex Biological Specimens using Nuclear Magnetic Resonance Spectroscopy -- Untargeted Metabolomics Methods to Analyze Blood Derived Samples -- Multi-Compartmental High-Throughput Metabolomics Based on Mass Spectrometry -- GC-MS Non-Targeted Metabolomics of Neural Tissue -- GC-MS of Pentafluourobenzyl Derivatives of Phenols, Amines, Carboxylic Acids -- GC-MS of tert-Butyldimethylsilyl (tBDMS) Derivatives of Neurochemicals -- UHPLC-MS/MS Method for Determination of Biologically Important Thiols in Plasma using New Derivatizing Maleimide Reagent -- Untargeted Metabolomics Determination of Postmortem Changes in Brain Tissue Samples by UHPLC-ESI-QTOF-MS and GC-EI-Q-MS -- Metallomics Imaging.
520 _aThis volume discusses the latest analytical approaches used to sample defined molecular populations of metabolites via functional group derivatization, specialized chromatographic methods, and ionization techniques. Chapters cover key methods for sample introductions to the ion source, including direct flow, gas chromatography, liquid chromatography, and capillary electrophoresis. Chapters also explore non-targeted and targeted analyses, as well as the emerging field of metallomics. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Metabolomics is a valuable resource for students, researchers, practicing physicians and veterinarians, and administrators involved in the funding of research.
988 _aSpringer_Protocols_2021
650 7 _2embne
_9138638
_aMetabolismo
776 0 8 _iPrinted edition:
_z9781071608630
776 0 8 _iPrinted edition:
_z9781071608654
776 0 8 _iPrinted edition:
_z9781071608661
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-0864-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b05/2023
_dz
_eIG
_zSI