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008			100301s2007 xxu| o |||| 0|eng d
020			_a9781597452441
024	7		_a10.1007/978-1-59745-244-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP171 _b2007 EB
245	0	0	_aMetabolomics : _bMethods and Protocols _cedited by Wolfram Weckwerth
250			_a1st edition 2007
264		1	_aTotowa, NJ _bHumana Press _c2007
300			_a1 recurso en línea (312 páginas) _b79 ilustraciones, 8 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v358
505	0		_aMetabolome Analysis Using Gas Chromatography Coupled to Mass Spectrometry -- Metabolite Profiling in Blood Plasma -- Nonsupervised Construction and Application of Mass Spectral and Retention Time Index Libraries From Time-of-Flight Gas Chromatography-Mass Spectrometry Metabolite Profiles -- Metabolomic Profiling of Natural Volatiles -- Metabolomics: Data Integration and Data Mining -- Integrative Profiling of Metabolites and Proteins -- Integrating Profiling Data -- Visualization and Analysis of Molecular Data -- A Gentle Guide to the Analysis of Metabolomic Data -- Capillary Electrophoresis Coupled to Mass Spectrometry -- Capillary Electrophoresis-Mass Spectrometry for Metabolomics -- Liquid Chromatography Coupled to Mass Spectrometry for Metabolomics and Structural Elucidation -- Application of Liquid Chromatography-Mass Spectrometry Analysis in Metabolomics -- Electrochemical Detection of Metabolites -- High-Performance Liquid Chromatography Separations Coupled With Coulometric Electrode Array Detectors -- Metabolic Fluxes -- Determination of Metabolic Flux Ratios From 13C-Experiments and Gas Chromatography-Mass Spectrometry Data -- Understanding the Roadmap of Metabolism by Pathway Analysis -- NMR Metabolome Analysis -- Revealing the Metabolome of Animal Tissues Using 1H Nuclear Magnetic Resonance Spectroscopy -- Nuclear Magnetic Resonance Metabonomics -- Practical Aspects of Uniform Stable Isotope Labeling of Higher Plants for Heteronuclear NMR-Based Metabolomics.
520			_aMetabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies. Part I of this volume focuses on GC-MS techniques; specifically, attention is given to metabolite profiling in blood plasma, construction and application of mass spectral and retention time index libraries, and metabolomic profiling of natural volatiles. In Part II, emphasis shifts to data integration and data mining techniques, and specific protocols discuss improving pattern recognition and biomarker selection for systems level approaches, and visualization and analysis of molecular and metabolomic data. Parts III, IV, and V examine the coupling of capillary electrophoresis and mass spectrometry, classical reversed phase liquid chromatography-mass spectrometry, and electrochemical detection of metabolites using HPLC separations coupled with coulometric electrode array detectors. In Part VI, protocols for the determination of metabolic flux rates are presented and a theoretical framework for metabolic pathway network analysis is provided. The volume concludes with an examination of cutting-edge NMR protocols.
988			_aSpringer_Protocols_2007
650		7	_2embne _9138638 _aMetabolismo
650		7	_2embne _9160489 _aBioinformática
776	0	8	_iPrinted edition: _z9781617376436
776	0	8	_iPrinted edition: _z9781588295613
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-244-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b05/2023 _dz _eb _zSI