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007			cr nn 008mamaa
008			230325s2011 sz | s |||| 0|eng d
020			_a9783031025839
024	7		_a10.1007/978-3-031-02583-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aR857.T55 _b2011 EB
100	1		_aBueno, Ericka M. _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9687584
245	1	0	_aBiologic Foundations for Skeletal Tissue Engineering _cby Ericka Bueno, Julie Glowacki
250			_a1st edition 2011
264		1	_aCham _bSpringer International Publishing _c2011
300			_a1 recurso en línea (IX, 215 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aSynthesis Lectures on Tissue Engineering _x1944-0308
505	0		_aIntroduction -- Structure and Function of Bone and Cartilage Tissue -- Development -- Responses to Injury and Grafting -- Clinical Applications for Skeletal Tissue Engineering -- Animal Models -- Tissue Engineering Principles for Bone and Cartilage -- Perspectives.
520			_aTissue engineering research for bone and joint applications entails multidisciplinary teams bringing together the needed expertise in anatomy, biology, biochemistry, pathophysiology, materials science, biomechanics, fluidics, and clinical and veterinary orthopedics. It is the goal of this volume to provide students and investigators who are entering this exciting area with an understanding of the biologic foundations necessary to appreciate the problems in bone and cartilage that may benefit from innovative tissue engineering approaches. This volume includes state-of-the-art information about bone and cartilage physiology at the levels of cell and molecular biology, tissue structure, developmental processes, their metabolic and structural functions, responses to injury, mechanisms of post-natal healing and graft incorporation, the many congenital and acquired disorders, effects of aging, and current clinical standards of care. It reviews the strengths and limitations of various experimental animal models, sources of cells, composition and design of scaffolds, activities of growth factors and genes to enhance histogenesis, and the need for new materials in the context of cell-based and cell-free tissue engineering. These building blocks constitute the dynamic environments in which innovative approaches are needed for addressing debilitating disorders of the skeleton. It is likely that a single tactic will not be sufficient for different applications because of variations in the systemic and local environments. The realizations that tissue regeneration is complex and dynamic underscore the continuing need for innovative multidisciplinary investigations, with an eye to simple and safe therapies for disabled patients. Table of Contents: Introduction / Structure and Function of Bone and Cartilage Tissue / Development / Responses to Injury and Grafting / Clinical Applications for Skeletal Tissue Engineering / Animal Models / Tissue Engineering Principles for Bone and Cartilage / Perspectives.
988			_aSynthesis Collection of Technology_2011
650		7	_2embne _9668849 _aTejidos (Biología)
650		7	_2embne _9313163 _aHuesos _xRegeneración
650		7	_2embne _9679376 _aCartílago _xRegeneración
700	1		_aGlowacki, Julie _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9687585
776	0	8	_iPrinted edition: _z9783031014550
776	0	8	_iPrinted edition: _z9783031037115
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-02583-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b03/2023 _dz _eIG _zSI