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008			230418s2021 sz | s |||| 0|eng d
020			_a9783031023880
024	7		_a10.1007/978-3-031-02388-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC262 _b2021 EB
100	1		_aMohammad-Hadi, Layla _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9688123
245	1	0	_aApplications of Minimally Invasive Nanomedicine-Based Therapies in 3D in vitro Cancer Platforms _cby Layla Mohammad-Hadi, Marym Mohammad-Hadi
250			_a1st edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XIII, 93 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aSynthesis Lectures on Materials and Optics _x2691-1949
505	0		_aPreface -- Acknowledgments -- Introduction -- Photodynamic Therapy and Photochemical Internalization -- Photosensitizers and Therapeutic Agents Used in PDT and PCI -- The Use of Nanoparticles in PDT and PCI -- 3D in vitro Cancer Models -- The Applications of PDT and PCI in 3D in vitro Cancer Models -- Authors' Biographies.
520			_aMinimally invasive techniques such as Photodynamic Therapy (PDT) and Photochemical Internalisation (PCI) have for years been under investigation for the treatment of solid cancers. A significant number of the recent research studies have applied PDT and PCI to biological three-dimensional (3D) cancer platforms with many of the studies also involving the use of nanoparticles in order to enhance the efficacy of these light-based therapies. Interest in the employment of 3D cancer platforms has increased considerably due to the ability of the platforms to mimic in vivo models better than the conventional two-dimensional (2D) cultures. Some of the advantages of the 3D cancer systems over their 2D counterparts include improved interaction between cancer cells and the surrounding extracellular matrix (ECM) as well as restricted drug penetration which would allow optimization of treatments prior to undertaking of in vivo studies. The different chapters of this book will discuss photosensitizers and nanoparticles used in PDT and PCI in addition to the applications of these treatments in various 3D cancer models.
988			_aSynthesis Collection of Technology_2021
650		7	_2embne _9174085 _aCáncer _xTratamiento
650		7	_2embne _9139308 _aCáncer _xFototerapia
650		7	_2embne _9445593 _aNanomedicina
700	1		_aMohammad-Hadi, Marym _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9688124
776	0	8	_iPrinted edition: _z9783031002526
776	0	8	_iPrinted edition: _z9783031012600
776	0	8	_iPrinted edition: _z9783031035166
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-02388-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b04/2023 _dz _eIG _zSI