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008			221210s2022 si | s |||| 0|eng d
020			_a9789811654190
024	7		_a10.1007/978-981-16-5419-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRB155.8 _b2022 EB
245	0	0	_aGene Delivery _cedited by Huayu Tian, Xuesi Chen
250			_a1st edition 2022
264		1	_aSingapore _bSpringer International Publishing _c2022
300			_a1 recurso en línea (233 illus., 60 illus. in color. eReference.
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	1		_aBiomaterial Engineering _x2523-8817
505	0		_aOverview on gene therapy -- Cationic liposome -- Functionalized peptide dendrimers -- Bioresponsive poly(amido amine)s -- Cationic polyphosphoesters -- Polysaccharide-based gene carriers -- Polypeptide-based gene carriers -- Fluorinated gene carriers -- Target gene delivery systems -- Cationic helical polypeptides -- Cyclic cationic polymers -- Cationic bolaamphiphile -- Chitosan-functionalized gene carriers -- Charge-reversal gene carriers -- Multifunctional envelope-type nanodevice -- Drug and gene co-delivery systems -- Oral delivery of gene therapy -- Gene therapy for brain diseases.
520			_aGene delivery is a promising strategy for the specific treatment of numerous gene-associated human diseases by intentionally altering the gene expression in pathological cells. A successful clinical application of gene-based therapy depends on an efficient gene delivery system. Many efforts have been attempted to improve the safety and efficiency of gene-based therapies. Nanoparticles have been proved to be the most promising vehicles for clinical gene therapy due to their tunable size, shape, surface, and biological behaviors. In this volume, the recent developments of nanoparticles for clinical gene therapy will be identified and summarized.
988			_aSpringer_Engineering_2022
650		7	_2embne _9150702 _aTerapia genética
650		7	_2embne _9150723 _aMateriales biomédicos
700	1		_aTian, Huayu _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aChen, Xuesi _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811654183
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-16-5419-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b12/2022 _dz _eIG _zSI