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005			20230102122142.0
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008			201012s2021 sz | s |||| 0|eng d
020			_a9783030536060
024	7		_a10.1007/978-3-030-53606-0 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC647 .C55 _b2021 EB
245	0	0	_aTrauma Induced Coagulopathy _cedited by Hunter B. Moore, Matthew D. Neal, Ernest E. Moore
250			_a2nd edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XIX, 802 páginas) _b33 illus
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
505	0		_aHistorical Perspective of Trauma Induced Coagulopathy -- Epidemiology of Hemorrhage-related Mortality -- Cell-Mediated Hemostasis -- Thrombin-Antithrombin System -- Physiology of Hemostasis: Plasmin-antiplasmin system -- Thrombin Formation -- Platelets -- Fibrinogen -- Defining and Assessing the Endotheliopathy of Trauma and its Implications on Trauma Induced Coagulopathy and Trauma Related Outcomes -- Protein C -- Fibrinolysis Dysregulation following Trauma -- Complement System -- Neutrophils, Inflammation and Innate Immunity in Trauma-Induced Coagulopathy -- Disseminated Intravascular Coagulation -- Grading Clinical Coagulopathy and Predicting Massive Transfusion -- Prothrombin and Partial Thromboplastin Time -- Fibrinogen Assays -- Rotational Thromboelastometry (ROTEM®) -- Thromboelastography (TEG® 5000 and TEG® 6s Hemostasis Analyzers with TEG Manager® Software) -- Red Blood Cell Transfusions -- Plasma Transfusion -- Cryoprecipitate/ Fibrinogen Concentrate Transfusions -- Platelet Transfusion -- Whole Blood for the Resuscitation of Massively Bleeding Civilian Patients -- Adjunct Factor Replacement -- Anti-fibrinolytics -- Ratio Driven Massive Transfusion Protocols -- Goal-Directed Massive Transfusion Management -- Pre-Hospital Resuscitation -- Venous Thromboembolism after Trauma -- Fibrinolysis Shutdown and Venous Thromboembolism -- Congenital and Acquired Hypercoagulable States -- Pediatrics -- Traumatic Brain Injury-Induced Coagulopathy -- Blunt Solid Organ Injury: A Call for Timely Chemoprophylaxis in the Setting of Early Hypercoagulability -- Pregnancy -- Liver Failure -- Pulmonary Coagulation in the Pathogenesis of Trauma-Associated Acute Respiratory Distress Syndrome -- Management of Chronically Anticoagulated Patients -- Randomized Controlled Trials: Informing Clinical Practice for Traumatically Injured Patients -- The Quantra® System and SEER Sonorheometry -- Dried Plasma for Trauma Resuscitation -- Synthetic Blood Substitutes -- Flow-Based Coagulation and Fibrinolysis Assays -- Animal Models of Coagulopathy -- Applications of Viscoelastic Hemostatic Assays at the Site of Care: Considerations and Implications.
520	3		_aThe first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
988			_aSpringer_Medicine_2021
650		7	_2embne _9674461 _aCoagulación sanguínea _xTrastornos
650		7	_2embne _9140367 _aTraumatología
700	1		_aMoore, Hunter B. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aNeal, Matthew D. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aMoore, Ernest E. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030536053
776	0	8	_iPrinted edition: _z9783030536077
776	0	8	_iPrinted edition: _z9783030536084
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-53606-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b11/2022 _dz _eu _zSI