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008			200929s2021 sz a o |||| 0|eng d
020			_a9783030531768
024	7		_a10.1007/978-3-030-53176-8 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC78.7.T62 _b2021 EB
245	0	0	_aPET and SPECT of Neurobiological Systems _cedited by Rudi A. J. O. Dierckx, Andreas Otte, Erik F. J. de Vries, Aren van Waarde, Adriaan A. Lammertsma
250			_a2nd edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XII, 1132 páginas) _b374 ilustraciones, 165 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
505	0		_aPART I BASICS: Animal Models for Brain Research -- Small Animal Molecular Imaging - μPET, μSPECT -- Cerebral Glucose Metabolism -- Cerebral Blood Flow Measurement with 15O-Water PET -- Principles of Brain Perfusion SPECT -- The Impact of Genetic Polymorphisms on Neuroreceptor Imaging -- PART II SYSTEMS: Acetylcholinesterase -- Adenosine Receptors -- Beta-Amyloid and Other Proteinopathies -- Central Benzodiazepine Receptors -- Cyclooxygenase-2 -- Dopamine System in Humans -- Endocannabinoid System -- Glutamate Receptors (Metabotropic) -- Histamine H3 Receptors -- Hormone Receptors (Steroids) -- Monoamine Oxidase B -- MRP1 Function in the BBB -- Neuroinflammation: From Target Selection to Preclinical and Clinical Studies -- Nicotinic Acetylcholine Receptors -- NMDA Receptors -- Norepinephrine Transporter -- Opioid Receptors -- P-Glycoprotein and Other ABC Transporters -- Phosphodiesterases -- Purinergic Receptors -- Serotonin System -- Serotonin Transporter and Monoamine Oxidase A -- Sigma-1 Receptors -- Sigma-2 Receptors -- Synaptic Density (SV2A) -- Tau Pathology -- Translocator Protein -- Tropomyosin Receptor Kinase -- Vesicular Acetylcholine Transporter -- Vesicular Monoamine Transporter.
520	3		_aThis book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, β-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
988			_aSpringer_Medicine_2021
650		7	_2embne _9159703 _aTomografía por emisión
650		7	_2embne _9139971 _aRadiología
700	1		_aDierckx, Rudi A. J. O. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _988797
700	1		_aOtte, Andreas P. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _988798 _d1967-
700	1		_aVries, Erik F. J. de _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9133684
700			_avan Waarde, Aren _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _988842
700	1		_aLammertsma, Adriaan A. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030531751
776	0	8	_iPrinted edition: _z9783030531775
776	0	8	_iPrinted edition: _z9783030531782
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-53176-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b10/2022 _dz _eb _zSI