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020 _a9783030569549
024 7 _a10.1007/978-3-030-56954-9
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC691
_b2021 EB
245 0 0 _aStem Cell Therapy for Vascular Diseases :
_bState of the Evidence and Clinical Applications
_cedited by Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik
250 _a1st edition 2021
264 1 _aCham
_bSpringer International Publishing
_c2021
300 _a1 recurso en línea (XII, 425 páginas)
_b46 ilustraciones, 38 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aarchivo de texto
_bPDF
505 0 _a1. Introduction to Stem Cell Therapy and its Application in Vascular Diseases -- 2. Types And Origin of Stem Cells -- 3. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease -- 4. The Ethical Challenges of Stem Cell Therapy in Vascular Disorders -- 5. Bone Marrow-Derived Cells: from the Laboratory to the Clinic -- 6. Angiogenesis: Perspectives From Therapeutic Angiogenesis -- 7. Stem Cell Therapy for Diabetic Foot Ulcers -- 8. Venous Foot and Leg Ulcers -- 9. Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells for Vascular Regeneration -- 10. Mesenchymal Stem Cell and Hematopoietic Stem Cell Transplantation for Vasculitis -- 11. Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger's Disease -- 12. Changing the Course of Peripheral Arterial Disease Using Adult Stem Progenitor Cells -- 13. Stem Cell Delivery for the Treatment of Arteriovenous Fistula Failure -- 14. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling -- 15. Stem Cell Therapy for Stroke -- 16. Use of Stem Cells in the Treatment of Erectile Dysfunction -- 17. Stem Cell Therapy for Ophthalmic Vascular Disease -- 18. Stem Cell Therapy Delivery in Liver Disease -- 19. Stem Cell Therapy for Lymphedema.
520 3 _aVascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.
988 _aSpringer_Medicine_2021
650 7 _2embne
_9668848
_aEnfermedades vasculares
650 7 _2embne
_9160528
_aCélulas madre
700 1 _aNavarro, Tulio Pinho
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMinchillo Lopes, Lara Lellis Navarro
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aDardik, Alan
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030569532
776 0 8 _iPrinted edition:
_z9783030569556
776 0 8 _iPrinted edition:
_z9783030569563
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-56954-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b10/2022
_dz
_eb
_zSI