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008			220415s2022 si | o |||| 0|eng d
020			_a9789811661327
024	7		_a10.1007/978-981-16-6132-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR74.8 _b2022 EB
245	0	0	_aNatural Products from Actinomycetes : _bDiversity, Ecology and Drug Discovery _cedited by Ravishankar V. Rai, Jamuna A. Bai
250			_a1st edition 2022
264		1	_aSingapore _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XIV, 508 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_aChapter 1. Dimensional Research on Actinomycetes -- Chapter 2. Isolation of Actinobacteria from uncommon habitats like insects and mollusks -- Chapter 3. Diversity, Chemical biology and Ecology of Actinomycetes and the Discovery of Natural Products -- Chapter 4. Actinobacteria from Arid Environments and their Biotechnological Applications -- Chapter 5. Endophytic actinobacteria in biosynthesis of bioactive metabolites and their application in improving crop yield and sustainable agriculture -- Chapter 6. An overview on natural product from endophytic actinomycetes -- Chapter 7. Regulation of Secondary Metabolites through Signaling Moleculesin Streptomyces -- Chapter 8. New strategies to activate secondary metabolism in Streptomyces -- Chapter 9. Novel Agroactive Secondary Metabolites from Actinomycetes in The Past Two Decades with Focus on Screening Strategies and Discovery -- Chapter 10. Quorum sensing and quorum quenching Metabolites in Actinomycetes -- Chapter 11. Metabolic engineering of Actinomycetes for natural product discovery -- Chapter 12. Application of CRISPR Cas9 editing for production of secondary metabolites in actinomycetes -- Chapter 13. Synthetic biology in actinomycetes for natural product discovery -- Chapter 14. Endophytic actinomycetes: secondary metabolites and genomic approaches -- Chapter 15. Mining for NRPS and PKS genes in Actinobacteria using Whole-genome sequencing and Bioinformatics Tools -- Chapter 16. Glycopeptide antibiotics: genetics, chemistry, new screening approaches -- Chapter 17. Biotechnological aspects of siderophore biosynthesis by actinobacteria -- Chapter 18. An overview of biomedical, biotechnological and industrial applications of Actinomycetes.-.
520			_aThis book provides in-depth information about the ecology, diversity and applications of Actinomycetes. The book is divided into two major parts. The first part discusses the diversity, chemical biology and ecology of Actinomycetes. It also covers the discovery of natural products from soil, endophytic and marine-derived Actinomycetes. It includes natural product discovery, chemical biology, new methods for discovering secondary metabolites, structure elucidation and biosynthetic research of natural products. The chapters in this part focus on the effects of biological and chemical elicitation at molecular level on secondary metabolism in Actinomycetes. The second part of the book discusses genomic and synthetic biology approaches in Actinomycetes drug discovery. This part includes chapters focused on the application of metabolic engineering to optimize natural product synthesis and the use of omics data in engineering of regulatory genes. It covers the advanced tools of synthetic biology and metabolic engineering including cluster assembly, CRISPR/Cas9 technologies, and chassis strain development for natural product overproduction in Actinomycetes. It describes the use of bioinformatics tools for reprogramming of biosynthetic pathways through polyketide synthase and non-ribosomal peptide synthetase engineering. These advanced genomic and molecular tools are expected to accelerate the discovery and development of new natural products from Actinomycetes with medicinal and other industrial applications. The book is useful to researchers and students in the field of microbiology, pharmaceutical sciences and drug discovery.
988			_aSpringer_BiomedLife_2022
650		7	_2embne _9138901 _aBacterias
650		7	_2embne _9137892 _aMedicamentos
700	1		_aRai, Ravishankar V. _eeditor literario
700	1		_aBai, Jamuna A. _eeditor literario
773	0		_tSpringer Nature eBook
776	0	8	_iPrinted edition: _z9789811661310
776	0	8	_iPrinted edition: _z9789811661334
776	0	8	_iPrinted edition: _z9789811661341
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-16-6132-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2022 _dz _eb _zSI