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003			ES-MaUEC
005			20230102122014.0
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007			cr nn 008mamaa
008			220408s2022 si | o |||| 0|eng d
020			_a9789811597817
024	7		_a10.1007/978-981-15-9781-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP363.5 _b2022 EB
245	0	0	_aProteins Associated with Neurodevelopmental Disorders _cedited by M. Walid Qoronfleh, Musthafa Mohamed Essa, Chidambaram Saravana Babu
250			_a1st edition 2022
264		1	_aSingapore _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XV, 339 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNutritional Neurosciences _x2730-6720
505	0		_aChapter 1. Proteins Commonly Linked to Autism Spectrum Disorder -- Chapter 2. Protein Aggregation and Recycling -- Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD -- Chapter 4. Proteomic profiling in children with ASD -- Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics -- Chapter 6. Chromatin and Epigenetic Regulation in ASD -- Chapter 7. Autism and the Scaffolding Protein Neurobeachin -- Chapter 8. Genomic Profiling in ADHD subjects -- Chapter 9. ADHD and Epigenetics Regulation -- Chapter 10. Proteomic Approach in ADHD -- Chapter 11. DHD and the Dopamine Transporter (DAT) -- Chapter 12. Protein Kinases involved in ADHD -- Chapter 13. ADHD and Cell Adhesion Molecule 1 - CAM 1 (CADM1 gene) -- Chapter 14. ASD and Cell Adhesion Molecule Astrotactin -- Chapter 15. Possible therapeutic interventions through proteins in ADHD.
520			_aThis book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
988			_aSpringer_BiomedLife_2022
650		7	_2embne _9160713 _aDesarrollo neurológico
650		7	_2embne _9139861 _aProteínas
700			_aQoronfleh, M. Walid _eeditor literario _9683525
700	1		_aEssa, Musthafa Mohamed. _eeditor literario
700			_aChidambaram, Saravana Babu _eeditor literario _9683524
773	0		_tSpringer Nature eBook
776	0	8	_iPrinted edition: _z9789811597800
776	0	8	_iPrinted edition: _z9789811597824
776	0	8	_iPrinted edition: _z9789811597831
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-9781-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2022 _dz _eb _zSI