000 04116nam a2200457 i 4500
999 _c382763
_d382763
001 382763
003 ES-MaUEC
005 20230102122013.0
006 a|||| o|||| 00| 0
007 cr nn 008mamaa
008 220329s2022 si | o |||| 0|eng d
020 _a9789811675898
024 7 _a10.1007/978-981-16-7589-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH588.S83
_b2022 EB
245 0 0 _aStem Cell Production :
_bProcesses, Practices and Regulations
_cedited by Firdos Alam Khan
250 _aFirst edition 2022
264 1 _aSingapore
_bSpringer International Publishing
_c2022
300 _a1 recurso en línea (XI, 272 páginas)
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
505 0 _aChapter 1. Stem Cell Therapy: Significance and Applications of Stem Cell Products in the Tissue Engineering and Regenerative Medicine -- Chapter 2. GLP Requirements of Stem Cells -- Chapter 3. Current Good Manufacturing Practice (CGMP) Facility and Production of Stem Cell -- Chapter 4. Global Regulatory Frameworks and Quality Standards for Stem Cells Therapy and Regenerative Medicines -- Chapter 5. Stem Cell Bioreactors: Design, Structure and Operation of Stem Cell Bioreactors -- Chapter 6. Stem Cell Culture and Expansion: Role of culture, Types of Cells, Growth Conditions, Media Nutrients, Growth Factors, Growth Phase Cycle -- Chapter 7. UP Scaling of Clinical Grade Stem Cell Production-Upstream Processing (USP) and Downstream Processing (DSP) Operations of Cell Expansion, Harvesting, Detachment, Separation, Washing and Concentration Steps, and the Regulatory Requirements -- Chapter 8. Characterization of Clinical-Grade Stem Cells: Microscopic, Cellular, Molecular, and Functional Characterization of Stem Cells and their Products According to Regulatory Requirements for FDA Approval -- Chapter 9. Stem Cell Safety and Sterility Testing: A Promising Approach in Regenerative Medicine -- Chapter 10. Stem Cells Storage, Packaging and Transportation -- Chapter 11. Stem Cell Clinical Trials and Stem Cell Market.-.
520 _aThis book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases. The book then reviews the recent developments in the cultivation of stem cells in bioreactors, including critical cultural parameters, possible bioreactor configuration and integrations of novel technologies in bioprocess developmental stages. The book also introduces microscopic, molecular, and cellular techniques for characterization of stem cells for regulatory approvals. Further, it describes optimal cell transporting conditions to maintain cell viability and properties. Further, it summarizes characterization strategies of clinical grade stem cells for stem cell therapy. This book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.
988 _aSpringer_BiomedLife_2022
650 7 _2embne
_9160528
_aCélulas madre
650 7 _2embne
_9140931
_aBiotecnología
700 1 _aKhan, Firdos Alam.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789811675881
776 0 8 _iPrinted edition:
_z9789811675904
776 0 8 _iPrinted edition:
_z9789811675911
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-16-7589-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b09/2022
_dz
_eb
_zSI