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008			220328s2022 sz | o |||| 0|eng d
020			_a9783030964054
024	7		_a10.1007/978-3-030-96405-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP551 _b2022 EB
245	0	0	_aProtein Reviews _nVolume 22 _cedited by M. Zouhair Atassi
250			_aFirst edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (VII, 132 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aProtein Reviews _x2520-1905 _v1371
505	0		_aIntegrated Structural Studies for Elucidating Carotenoid-Protein Interactions -- The Non-continuum Nature of Eukaryotic Transcriptional Regulation -- Photoreceptor Phosphodiesterase (PDE6): Structure, Regulatory Mechanisms, and Implications for Treatment of Retinal Diseases -- Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa -- Elasticity-Associated Functionality and Inhibition of the HIV Protease -- Single-Run Catalysis and Kinetic Control of Human Telomerase Holoenzyme.
520			_aThe Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein structure, function, evolution and genetics. Volumes are published online first, prior to publication in a printed book. Chapters are selected according to their importance to the understanding of biological systems, relevance to the unravelling of issues associated with health and disease, or impact on scientific or technological advances and developments. Volume 22 presents six review chapters authored by experts in related fields. The first chapter covers carotenoid-protein interactions. Chapter two addresses the non-continuum of eukaryotic transcriptional regulation. The third chapter reviews the structure of the regulatory and catalytic domains of the photoreceptor phosphodiesterase (PDE6) holoenzyme. Chapter four reviews the current knowledge on small molecule compounds that have been evaluated as rhodopsin modulators to be considered as leads for the development of novel therapies for retinitis pigmentosa. Chapter five deals with Plasticity-associated functionality and inhibition of the HIV protease. Finally, chapter six covers single-run catalysis and kinetic control of human telomerase holoenzyme. This volume is intended for research scientists, clinicians, physicians and graduate students in the fields of biochemistry, cell biology, molecular biology, immunology and genetics. .
988			_aSpringer_BiomedLife_2022
650		7	_2embne _9139861 _aProteínas
700	1		_aAtassi, M. Zouhair. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
773	0		_tSpringer Nature eBook
776	0	8	_iPrinted edition: _z9783030964047
776	0	8	_iPrinted edition: _z9783030964061
776	0	8	_iPrinted edition: _z9783030964078
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-96405-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2022 _dz _eb _zSI