000 03814nam a2200421 i 4500
999 _c382707
_d382707
001 382707
003 ES-MaUEC
005 20230102122006.0
006 a|||| o|||| 00| 0
007 cr nn 008mamaa
008 220307s2022 sz | o |||| 0|eng d
020 _a9783030878214
024 7 _a10.1007/978-3-030-87821-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP620
_b2022 EB
245 0 0 _aTranscriptomics in Health and Disease
_cedited by Geraldo A. Passos
250 _a2nd edition 2022
264 1 _aCham
_bSpringer International Publishing
_c2022
300 _a1 recurso en línea (XI, 474 páginas)
_b67 ilustraciones, 62 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
505 0 _a1. What is the transcriptome and how it is evaluated? -- 2. ALTERNATIVE SPLICING OF PRE-MESSENGER RNA -- 3. Transcriptome Analysis Using RNA-seq and scRNA-seq -- 4. TRANSCRIPTOMICS OF NEONATAL AND INFANT HUMAN THYMUS -- 5. Transcriptomics at the single cell level and human diseases: opportunities and challenges in data processing and analysis -- 6. METHODS FOR GENE CO-EXPRESSION NETWORK VISUALIZATION AND ANALYSIS -- 7. Comparative Analysis of Packages and Algorithms for the Analysis of Spatially Resolved Transcriptomics Data -- 8. The Interplay Between the Transcriptomics and Proteomics Profiles -- 9. TRANSCRIPTOME DURING NORMAL CELL DIFFERENTIATION -- 10. Transcriptomics to dissect the Immune System -- 11. Transcriptome Profiling in Autoimmune Diseases -- 12. Transcriptome Profiling in Experimental Inflammatory Arthritis -- 13. TRANSCRIPTOMICS AND IMMUNE RESPONSE IN HUMAN CANCER -- 14. MicroRNAs in Cancer -- 15. Oxidative Stress, DNA Damage and Transcriptional Expression of DNA Repair and Stress Response Genes in Diabetes Mellitus -- 16. Large-scale gene expression in monogenic and complex genetic diseases -- 17. Transcriptome in Human Mycoses -- 18. Understanding Chagas Disease by Multi-omics data Integration, Functional and Enrichment Computational Analysis.
520 _aThe study of transcriptomics is key to understanding complex diseases. This new edition will build on the foundation of the first edition while incorporating the progress that has been made in the field of transcriptomics in the past six years, including bioinformatics for data analysis. Written by leading experts, chapters address new subjects such as methodological advances in large-scale sequencing, the sequencing of single-cells, and spatial transcriptomics. The new edition will address how transcriptomics may be used in combination with genetic strategies to identify causative genes in monogenic and complex genetic diseases. Coverage will also explore transcriptomics in challenging groups of diseases, such as cancer, inflammation, bacterial infection, and autoimmune diseases. The updated volume will be useful for geneticists, genome biologists, biomedical researchers, molecular biologists, bioinformaticians, and students, among others.
988 _aSpringer_BiomedLife_2022
650 7 _2embne
_9140525
_aÁcidos nucleicos
700 _aPassos, Geraldo A.
_eeditor literario
_986874
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030878207
776 0 8 _iPrinted edition:
_z9783030878221
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-87821-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b09/2022
_dz
_eb
_zSI