000			03754nam a22004335i 4500
999			_c382019 _d382019 _x1
001			382019
003			ES-MaUEC
005			20230102121947.0
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008			220924s2022 sz | s |||| 0|eng d
020			_a9783030939908
024	7		_a10.1007/978-3-030-93990-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC642 _b2022 EB
245	0	0	_aAdvances in Hemophilia Treatment : _bFrom Genetics to Joint Health _cedited by E. Carlos Rodríguez-Merchán
250			_aFirst edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (VIII, 173 páginas) _b42 ilustraciones, 31 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_a1. Pathophysiology of hemophilia -- 2. Genetics of Hemophilia A and B -- 3. Inhibitors in Hemophilia A -- 4. Immune Tolerance In Patients with Hemophilia A -- 5. Hemophilia A: New drugs -- 6. Inhibitors in Hemophilia B -- 7. Immune Tolerance Induction in Hemophilia B -- 8. Hemophilia B: New Drugs -- 9. Management of Hemophilia Carriers -- 10. Pharmacoeconomic Aspects in Hemophilia -- 11. Assessment of Joint Health and Outcome Measures in Hemophilia -- 12. Musculoskeletal Medicine in Hemophilia -- 13. Management of Acute Hemarthrosis in Hemophilia (Including Joint Aspiration) -- 14. Hemophilic Arthropathy: Radiosynovectomy -- 15. Hemophilic Arthropathy: Arthroscopic Joint Debridement -- 16. Hemophilic Arthropathy: Total Joint Arthroplasty -- 17. Hemophilic Arthropathy: Other Orthopedic Procedures -- 18. Gene Therapy in Hemophilia: Latest Advances -- 19.A Summary of the Recent Recommendations of the WFH.
520			_aThis book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations. The first part is devoted to the disease's pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy - including replacement and non-replacement therapy - and gene therapy, as well as quality of life issues - also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement. Written by experts drawn from leading institutions involved in treatment of hemophilia and related joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.
988			_aSpringer_Medicine_2022
650		7	_2embne _9672556 _aHemofilia
650		7	_2embne _9168800 _aArticulaciones _xEnfermedades
700	1		_aRodríguez-Merchán, E. Carlos _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
773	0		_tSpringer Nature eBook
776	0	8	_iPrinted edition: _z9783030939892
776	0	8	_iPrinted edition: _z9783030939915
776	0	8	_iPrinted edition: _z9783030939922
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-93990-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2022 _dz _eIG _zSI