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008			220227s2022 sz | s |||| 0|eng d
020			_a9783030920340
024	7		_a10.1007/978-3-030-92034-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH324.2 _b2022 EB
245	1	0	_aLong Noncoding RNA : _bMechanistic Insights and Roles in Inflammation _cedited by Susan Carpenter.
250			_aFirst edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (IX, 189 páginas) _b12 ilustraciones, 11 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x2214-8019 _v1363
505	0		_aSection 1: Overview -- Chapter 1: Introduction and overview -- Section 2: Basics of long noncoding RNA Classifications and functions -- Chapter 2: The Complexity of the Mammalian Transcriptome -- Chapter 3: Towards molecular mechanism in long non-coding RNAs: linking structure and function -- Section 3: Long noncoding RNA and inflammation -- Chapter 4: Long noncoding RNAs in Rheumatology -- Chapter 5: LncRNA and Cardiovascular Disease -- Chapter 6: A role for lncRNAs in regulating inflammatory and autoimmune responses underlying type 1 diabetes -- Section 4: Long noncoding RNAs as Therapeutic targets -- Chapter 7: LncRNA Biomarkers of Inflammation and Cancer -- Chapter 8: Functional Implications of Intergenic GWAS SNPs in Immune Related lncRNAs -- Chapter 9: Long noncoding RNAs as Therapeutic Targets -- Section 5: Challenges and Future Directions -- Chapter 10: Challenges and future directions for LncRNAs and inflammation.
520			_aThis book brings together what is currently known in terms of basic research in the field of long noncoding RNAs (lncRNAs) and builds on this to delve more deeply in the specific roles that lncRNAs are playing during inflammation. The book provides readers with basic knowledge on lncRNAs: from understanding the complexity of the transcriptome, conservation, structure and the tools used to investigate these aspects, to how we use this information to study lncRNAs in a specific biological context. The volume covers the emerging roles of lncRNAs in the initial stages of inflammation as well as their roles in specific inflammatory diseases including arthritis, lupus, diabetes and cardiovascular disease. The book also shows the emerging interest in using lncRNAs as a therapeutic target and how this could impact our ability to diagnose and treat inflammatory diseases in the future.
988			_aSpringer_BiomedLife_2022
650		7	_2embne _9160489 _aBioinformática
700	1		_aCarpenter, Susan _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9683463
776	0	8	_iPrinted edition: _z9783030920333
776	0	8	_iPrinted edition: _z9783030920357
776	0	8	_iPrinted edition: _z9783030920364
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-92034-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2022 _dz _ep