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008			220131s2022 si | s |||| 0|eng d
020			_a9789811594113
024	7		_a10.1007/978-981-15-9411-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aR852 _b2022 EB
245	1	0	_aHandbook of Oxidative Stress in Cancer: Mechanistic Aspects _cedited by Sajal Chakraborti, Bimal K. Ray, Susanta Roychoudhury.
250			_aFirst edition 2022
264		1	_aSingapore _bSpringer International Publishing _c2022
300			_a1 recurso en línea (388 illus., 324 illus. in color. eReference.
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
505	0		_aInvolvement of ROS in thyroid cancer -- Skin cancer induced by pollution-medicated ROS -- Roles of β-Glucans in Oxidative Stress and Cancer -- Oxidative stress in glioma and its microenvironment -- Reactive oxygen species and their contribution to carcinogenesis -- Oral cancer and oxidative stress -- Oxidative stress in genitourinary cancer -- Oxidative stress in oral cancer -- Oxidative stress and glyoxalase pathway in cancer -- ROS and EMT in multistep carcinogenesis -- Functional regulation between matrix metalloproteases and cell junction proteins in gastric cancer -- Association of oxidative stress and mitochondrial dysfunction to gynaecological malignancies -- Impact of Caenorhabdits elegans in cancdeer drug resistance and development -- Pharmacology of natural products specifically plant based mitigating cisplatin-induced cardiotoxicity and attenuating oxidative stress, inflammation and associated signalling pathways -- Scafold based selective ROS generation as viable therapeutic strategies.
520			_aThis comprehensive, up-to-date reference work compiles the scientific research on the relationship between various forms of cancer and reactive oxygen species (ROS). It is well known that ROS play a key role in the various steps leading to malignancy, this includes increase in DNA mutation rates. The book brings together exciting reviews, written by leading experts all over the world. The book is divided into four broad sections. Each section describes the role of oxidative stress and underlying mechanisms and pathways, at various stages of cancer, including its role in carcinogenesis, cancer progression and metastasis. Further, the book describes how the reactive oxygen species (ROS) modulate gene expression and signal transduction pathways in cancer. The book discusses the ways to interfere with the cancer progression, and design of anti-cancer drugs. The book provides an integrated approach for better understanding of the development phases of oxidative stress-induced cancers, and mainly the current perspectives about mechanistic aspects of cancer initiation, progression and metastasis. It is a highly resourceful book and would be extremely important to clinicians, students and researchers in the field of cancer genetics, therapeutics and oncology.
988			_aSpringer_BiomedLife_2022
650		7	_2embne _9168783 _aMedicina _xInvestigación
700			_aChakraborti, Sajal _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _984935
700			_aRay, Bimal K. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9683404
700			_aRoychoudhury, Susanta _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9683405
776	0	8	_iPrinted edition: _z9789811594106
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-9411-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2022 _dz _ep _zSI