000			04688nam a22004095i 4500
999			_c368021 _d368021 _x1
001			368021
003			ES-MaUEC
005			20230102121659.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			220129s2022 si | s |||| 0|eng d
020			_a9789811658358
024	7		_a10.1007/978-981-16-5835-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH324 _b2022 EB
245	1	0	_aActinobacteria : _bMicrobiology to Synthetic Biology _cedited by Loganathan Karthik.
250			_aFirst edition 2022
264		1	_aSingapore _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XV, 276 páginas) _b1 ilustraciones
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
505	0		_aChapter 1. Actinomycetes: Microbiology to Systems Biology -- Chapter 2. Diversity of actinobacteria in various habitats -- Chapter 3. Traditional Screening and Genome Guided Screening of Natural Products from Actinobacteria -- Chapter 4. The relationship between actinobacteria and rice -- Chapter 5.Non-ribosomally and ribosomally synthesized bioactive peptides - NRPS and RiPPs from actinobacteria -- Chapter 6. Genome Data Mining, Chemistry and Bioactivity of Sesquiterpenes from Actinobacteria -- Chapter 7. Genome Data Mining, Chemistry and Bioactivity of Sesquiterpenes from Actinobacteria -- Chapter 8. Cloning and Heterologous expression of Natural products from Actinobacteria -- Chapter 9. Synthetic Biology and Metabolic Engineering in Actinobacteria for Natural Product Production -- Chapter 10. CRISPR ERA: CURRENT APPLICATIONS AND FUTURE PERSPECTIVES ON ACTINOBACTERIA -- Chapter 11. Uncultured Actinobacteria and Reverse engineering and Artificial Intelligence role in future -- Chapter 12. Cultivation and Diversity of Marine Actinomycetes: Molecular Approaches and Bioinformatics Tools -- Chapter 13. Antimicrobial Potential and Metabolite Profiling of Marine Actinobacteria -- Chapter 14. Pharmacology of FDA Approved Medicines from Actinobacteria.
520			_aThis book summarizes the basics of actinobacteria, from microbiology to synthetic biology. It focuses on diversity, NRPS, sesquiterpenes, lantipeptide, bioinformatics apparatuses, cloning, CRISPR, reverse engineering, FDA supported medications, and marine actinobacteria. It also covers the latest trends in drug discovery from actinobacteria, and introduces several recently developed bioinformatics and synthetic biology tools to explore new antibiotics from actinobacteria. Many natural products such as polyketides, isoprenoids, phenazines, peptides, indolocarbarbazoles, sterols, and others have been isolated and characterized from actinobacteria. Some products are synthesized by the non-ribosomal peptide synthetases (NRPSs), polyketide synthases (PKSs), or other functional genes. Although genome sequencing has uncovered the differing qualities of these chemicals, recognizing new items and their biosynthetic pathways is still under examination. Cryptic metabolic pathways have been explored using molecular techniques or culture-dependent approaches. In recent years, researchers' primary interest is to identify the specific conditions or agents that wake the cryptic antibiotics. Several bioinformatics and synthetic biology tools were developed to explore new antibiotics from actinobacteria. The book comprises 14 chapters with different aspects of application and utilization of actinomycetes from the microbiology; systems biology, pharmacology of natural products, bioinformatics, actinomycete and its diversity, CRISPR, artificial Intelligence, synthetic biology, metabolic engineering, expressional studies, and biosynthetic gene clusters. The book delivers useful information on actinomyces to researchers, novices in genome designing, specialists, clinicians, policymakers, and professionals.
988			_aSpringer_BiomedLife_2022
650		7	_2embne _9138150 _aBiología
700			_aKarthik, Loganathan _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9683391
776	0	8	_iPrinted edition: _z9789811658341
776	0	8	_iPrinted edition: _z9789811658365
776	0	8	_iPrinted edition: _z9789811658372
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-16-5835-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2022 _dz _ep _zSI