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008			211009s2021 sz a s |||| 0|eng d
020			_a9783030783112
024	7		_a10.1007/978-3-030-78311-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC643 _b2021 EB
245	0	0	_aBiology and Treatment of Leukemia and Bone Marrow Neoplasms _cedited by Vinod Pullarkat, Guido Marcucci
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
264		4	_c2021
300			_a1 recurso en línea (VIII, 196 páginas) _b17 ilustraciones, 14 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aCancer Treatment and Research _x2509-8497 _v181
505	0		_aAdvances in diagnosis and risk stratification of leukemias and bone marrow neoplasms -- Genetics and diagnostic approach to lymphoblastic leukemia -- Acute promyelocytic leukemia: update on risk stratification and treatment -- Current and emerging therapies for AML -- Current management and new developments in treatment of ALL -- Contemporary therapy of CML -- MDS: Pathogenesis and therapy -- Chronic lymphocytic leukemia: Biology and therapy -- Biology and current treatment of Myeloproliferative neoplasms -- Systemic Mastocytosis: Pathology and treatment -- Adoptive T-cell therapy and other novel immunotherapies for leukemia.
520			_aThis book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.
988			_aSpringer_Medicine_2021
650		7	_2embne _9140673 _aLeucemia
700	1		_aPullarkat, Vinod _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9682429
700	1		_aMarcucci, Guido _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9682430
776	0	8	_iPrinted edition: _z9783030783105
776	0	8	_iPrinted edition: _z9783030783129
776	0	8	_iPrinted edition: _z9783030783136
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-78311-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _ek _zSI