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008			210531s2021 sz | o |||| 0|eng d
020			_a9783030740962
024	7		_a10.1007/978-3-030-74096-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRD59 _b2021 EB
100	1		_aEvora, Paulo Roberto Barbosa _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9682392
245	1	0	_aVasoplegic Endothelial Dysfunction : _bCirculatory Shock and Methylene Blue _cby Paulo Roberto Barbosa Evora, Andrea Carla Celotto, Agnes Afrodite Sumarelli Albuquerque, Patricia Martinez Évora.
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XXIII, 144 páginas) _b14 ilustraciones, 3 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
505	0		_aPart I - General Conceptual Aspects -- Introduction -- Physiology of the Endothelium -- PART 2- PARTICULARITIES OF ENDOTHELIAL DYSFUNCTION IN DIFFERENT TYPES OF SHOCK -- Circulatory Shock: A Conceptual and Practical Approach -- Circulatory Shock, Ischemia Reperfusion Injury, Inflammatory Response Syndrome (SIRS) and Multiple Organ Failure -- Endothelial Dysfunction in Hemorrhagic Shock -- Endothelial Dysfunction in Cardiogenic Shock -- Endothelial Dysfunction in Distributive Shock -- PART 3- METHYLENE BLUE -- Methylene blue -- The Inhibition of Guanylate Cyclase by Methylene Blue as Therapeutic Proposal for Vasoplegia Associated with Shock -- Methylene Blue in the Treatment of Anaphylaxis -- Methylene Blue in Children and Neonates -- Methylene Blue and Burns -- Cardiac arrest and neuroprotection by methylene blue -- Methylene Blue and Endocarditis -- PART 4 - ENDOTHELIAL DYSFUNCTION IN SPECIFIC SITUATIONS -- Vasoplegic syndrome in heart surgery -- Vasoplegic Endothelial Dysfunction In Orthotopic Liver Transplantation -- Acid-base Balance -- The therapeutic use of inhaled nitric oxide.
520			_aThis unique work presents one of the most significant organ failure condition - cardiocirculatory shock - and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors' consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. This book´s translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.
988			_aSpringer_Medicine_2021
650		7	_2embne _9673726 _aShock traumático
650		7	_2embne _9138499 _aCirugía
700	1		_aCelotto, Andrea Carla _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9682393
700	1		_aSumarelli Albuquerque, Agnes Afrodite _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9682394
700	1		_aMartinez Évora, Patricia _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9682395
776	0	8	_iPrinted edition: _z9783030740955
776	0	8	_iPrinted edition: _z9783030740979
776	0	8	_iPrinted edition: _z9783030740986
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-74096-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _eb _zSI