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020			_a9783030698522
024	7		_a10.1007/978-3-030-69852-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC280.H4 _b2021 EB
245	0	0	_aEarly Detection and Treatment of Head & Neck Cancers . _bTheoretical Background and Newly Emerging Research _cedited by Rami El Assal, Dyani Gaudilliere, Stephen Thaddeus Connelly
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
264		4	_c2021
300			_a1 recurso en línea (XVI, 224 páginas) _b61 ilustraciones, 57 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
505	0		_aEpidemiology of Head and Neck Cancers -- Epidemiology of Head and Neck Premalignant Lesions -- Mutational Landscape of Head and Neck Cancers -- Genomic and Proteomic Factors of Head and Neck Cancer Progression -- Understanding the Role of Exosomes in Molecular Pathogenesis of Cancers including Head and Neck Cancers -- Risk of Head and Neck Cancers in Systemic Inflammatory Disorders and after Immunosuppressive Treatment -- Metastasis of Brain Tumors (including Glioblastoma) to Head and Neck Region -- Virus-associated Head and Neck Cancers in Immunocompromised and Healthy Patients -- Orofacial Pain-/Oral Adverse Event-associated with Head and Neck Cancers -- EGFR Activation Signature and Modulation in Head and Neck Cancers -- Identification of Genetic Differences between Normal and Tumor Tissues in Head and Neck Cancers -- Cellular Immune Mechanisms of Natural Killer (NK) Cell, Dendritic Cells (DC) and T Lymphocyte Activation Against Head and Neck Cancers -- Statistical Power Analysis in Head and Neck Cancer Studies -- Bioethics in Head and Neck Cancer Research -- Future Perspective of Head and Neck Cancer Research.
520			_aHead and neck cancer (HNC) is a heterogeneous group of cancers that, if combined, represent one of the most common cancer types. Patients with HNC suffer significant morbidity and mortality due to the importance of the structures involved. Over two-thirds of these patients are diagnosed at a late stage, leading to a poor prognosis. Therefore, advancements in early detection and treatment of HNC are crucial. This second volume provides an up-to-date overview of the theoretical background in the field of head and neck cancer (HNC) as well as of the emerging research that is impacting our understanding of this disease. The book begins with a comprehensive review of the epidemiology, etiology, symptoms, diagnosis, and staging of HNC. Next, it covers the essentials of potentially malignant disorders of the oral cavity, an important variety of HNC. Subsequently, it covers the newly emerging research in the field of HNC. The overall goal is to shift towards precision medicine (discussed in detail in Volume I), which will bring individualized clinical benefit to patients with HNC. This second volume of Early Detection and Treatment of Head & Neck Cancers concludes with the topic of chronic pain associated with HNC, including both the mechanisms of pain and the management strategies, and the emerging oral mucoadhesive drug delivery approach for HNC. All HNC surgeons, scientists, residents, and individuals whose lives have been touched by this disease, will recognize the impact pain has upon a patient's health and his or her recovery trajectory.
988			_aSpringer_Medicine_2021
650		7	_2embne _9210886 _aCabeza _xCáncer
700	1		_aEl Assal, Rami _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aGaudilliere, Dyani _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aConnelly, Stephen Thaddeus _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030698515
776	0	8	_iPrinted edition: _z9783030698539
776	0	8	_iPrinted edition: _z9783030698546
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-69852-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _ek _zSI