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020 _a9783030691707
024 7 _a10.1007/978-3-030-69170-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC280.B7
_b2021 EB
245 0 0 _aPrecision Molecular Pathology of Glioblastoma
_cedited by José Javier Otero, Aline Paixao Becker
250 _aFirst edition 2021
264 1 _aCham
_bSpringer International Publishing
_c2021
264 4 _c2021
300 _a1 recurso en línea (XV, 266 páginas)
_b62 ilustraciones, 55 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aMolecular Pathology Library
_x1935-987X
505 0 _aPart I: General Principles -- Epidemiology and etiology of glioblastoma -- The role of Molecular Genetics of Glioblastoma in the Clinical Setting -- Neurosurgical Approach to the Patient with Glioblastoma -- Machine Learning Approaches Pertinent to Glioma Classification -- Histopathology of Adult and Pediatric Glioblastoma -- Principles of Radiation Therapy for Glioblastoma Patients -- 'Implementing Molecular Pathology in a Developing Country -- Part II: Molecular Pathology of Glioblastoma -- Molecular Stratification of Adult and Pediatric High Grade Gliomas -- Genomic Heterogeneity of Aggressive Pediatric and Adult Diffuse Astrocytomas -- Immunohistochemical Surrogates for Molecular Pathology -- Part III: Key Molecular Pathways in Glioblastoma Development and Progression -- Learning-Based Automated Methods for Brain Tumor Segmentation, Subtype Classification, Tracking and Patient Survival Prediction -- Rodent Brain Tumor Models for Neuro-Oncology Research -- Stem cell based modelling of glioblastoma -- The Neuroscience of Glioblastoma.
520 _aThis volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists. The book reviews basic principles such as epidemiology and etiology, and modern 2016 WHO classification of CNS tumors. Chapters cover a general overview of common molecular techniques used in molecular pathology, molecular pathology in a developing country, key drivers of patient outcomes and predictors of response to radiation and/or chemotherapy treatment, and immunohistochemical surrogates for key molecular pathology. It concludes with reviews on radiomics, animal and stem cell models of glioblastoma, and a chapter on the emerging field of Glioblastoma Neuroscience. Precision Molecular Pathology of Glioblastoma is intended for pathology residents and fellows interested in glioblastoma, general surgical pathologists who need reviews on how to implement modern glioblastoma classification, as well as neuro-radiologists, oncologists, and radiation oncologists needing a holistic perspective to glioblastoma diagnosis and management.
988 _aSpringer_Medicine_2021
650 7 _2embne
_9214753
_aCerebro
_xTumores
700 1 _aOtero, José Javier
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBecker, Aline Paixao
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030691691
776 0 8 _iPrinted edition:
_z9783030691714
776 0 8 _iPrinted edition:
_z9783030691721
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-69170-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2022
_dq
_ek
_zSI