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008			210722s2021 gw | o |||| 0|eng d
020			_a9783030762018
024	7		_a10.1007/978-3-030-76201-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC346 _b2021 EB
245	0	0	_aChordoma of the Spine : _bA Comprehensive Review _cedited by Daniel M. Sciubba, Joseph H. Schwab
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XX, 307 páginas) _b96 ilustraciones, 62 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
505	0		_aSection I Pathophysiology and Molecular Mechanisms of Chordoma -- Notochordal Morphogenesis and the Origin of Chordoma -- Molecular and Genetic Mechanisms of Spinal Chordoma -- Section II Epidemiology, Clinical History, and Work-Up for Chordoma.-Historical Overview, Demographics, and Clinical Presentation of Spinal Chordoma -- Clinical Work up, Diagnostic Imaging and Biopsy -- Histopathologic Classification of Spinal Chordoma -- Multi-disciplinary Planning for Treatment -- Section III Surgical Management of Chordoma -- Surgical Management of Chordoma of the Occipitocervical Junction -- Surgical Management of Chordoma of the Cervical Spine -- Surgical Management of Chordoma of the Thoracic Spine -- Surgical Management of Chordoma of the Lumbar Spine -- Surgical Management of Chordoma of the Sacrum -- Soft Tissue Reconstruction Following Surgery for Sacral Chordoma -- Vascular Reconstruction After EnBloc Resection -- Section IV Radiation and Chemotherapeutic Adjuvants for Chordoma -- Photon Therapy for Chordoma of the Spine -- Heavy Particle Therapy for Chordoma -- Systemic Therapy, Trials and Future Directions for Chordoma of the Spine -- Index.
520			_aThis book provides a comprehensive review of the epidemiology, pathogenesis, diagnosis, and management of chordomas of the mobile spine and sacrum. Historically, knowledge about how to deliver such state-of-the-art care has not been widespread, resulting in inconsistent treatment, and, all too often, suboptimal outcomes for chordoma patients. This text is an important step towards broadening that knowledge, and, in turn, improving the care provided to chordoma patients. The book is divided into 4 parts comprising 16 chapters. The first part focuses on the pathophysiology and molecular drivers of chordoma. The second focuses on the epidemiology and clinical history, as well as the histological, oncologic, and radiographic work-up of chordoma. The third part focuses primarily on the technical aspects of surgery for chordoma. It is broken down by anatomic region, with the final two chapters focusing on the soft tissue and bony reconstruction following chordoma resection. The last part focuses on the exciting field of adjuvant therapies for chordoma. This includes both radiation therapies and novel chemotherapeutic options for recurrent, metastatic, and dedifferentiated chordoma. Written by world experts from leading chordoma centers, Chordoma of the Spine serves as a valuable reference for spinal oncologists and general spine surgeons who may encounter chordoma patients in their practice. It provides the most up-to-date evidence regarding all aspects of treating patients with this disease. By focusing on this specific pathology of the spine, this resource condenses expert-level research into understandable treatment algorithms.
988			_aSpringer_Medicine_2021
650		7	_2embne _aSistema nervioso _xEnfermedades _9169088
700	1		_aSciubba, Daniel M. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aSchwab, Joseph H. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030762001
776	0	8	_iPrinted edition: _z9783030762025
776	0	8	_iPrinted edition: _z9783030762032
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-76201-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _eb _zSI