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008			210305s2021 si | s |||| 0|eng d
020			_a9789813360136
024	7		_a10.1007/978-981-33-6013-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC280.G5 _b2021 EB
245	0	0	_aMolecular Diagnosis and Targeting for Gynecologic Malignancy _cedited by Seiji Isonishi, Yoshihiro Kikuchi
250			_aFirst edition 2021
264		1	_aSingapore _bSpringer International Publishing _c2021
300			_a1 recurso en línea (VIII, 165 páginas) _b26 ilustraciones, 24 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aCurrent Human Cell Research and Applications, _x2522-0748
505	0		_a1. Cancer Stem Cells in gynecologic cancer -- 2. Patient-derived xenograft models in gynaecological malignancies -- 3. Cancer genomic profiling of gynecological malignancies by Todai OncoPanel, a twin DNA and RNA panel -- 4. Investigating the molecular carcinogenesis of ovarian high-grade serous cancer -- 5. The role of G protein-coupled receptor signaling in gynecologic malignancy -- 6. Tailor-made therapy according genetic alteration in epithelial ovarian cancers -- 7. Signaling and drug resistance -- 8. Molecular analysis in endometrial carcinoma -- 9. Molecular Landscape in Ovarian Clear Cell Carcinoma -- 10. Molecular pathology and clinicopathological significance of endometrial carcinoma -- 11. Novel approach for therapeutics of cervical cancer based on HPV-associated carcinogenesis at the cervix -- 12. Hereditary gynecological malignancy and molecular features.
520	3		_aThis book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.
988			_aSpringer_Medicine_2021
650		7	_2embne _9172317 _aAparato genital femenino _xCáncer
650		7	_2embne _9139477 _aCitología
650		7	_2embne _aOncología _xInvestigación _9139207
650		7	_2embne _9138562 _aGinecología
700	1		_aIsonishi, Seiji _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9681941
700	1		_aKikuchi, Yoshihiro _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9681943
776	0	8	_iPrinted edition _z9789813360129
776	0	8	_iPrinted edition _z9789813360143
776	0	8	_iPrinted edition _z9789813360150
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-33-6013-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _esc _zSI