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008			210805s2021 sz | s |||| 0|eng d
020			_a9783030717377
024	7		_a10.1007/978-3-030-71737-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH324.2 _b2021 EB
245	0	0	_aEvolutionary Systems Biology : _bAdvances, Questions, and Opportunities _cedited by Anton Crombach
250			_aSecond edition 2021
264		1	_aCham _bSpringer International Publising _c2021
300			_a1 recurso en línea (X, 294 páginas) _b49 ilustraciones, 31 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
490	0		_aComputer Science (SpringerNature-11645)
490	0		_aComputer Science (R0) (SpringerNature-43710)
505	0		_aPart 1. Theory and philosophy -- Biology as a process and the consequences for studying it -- Capturing the genotype-phenotype map with the adaptive multiscape -- Evolution plays a high-dimensional game -- What is next for evolutionary systems biology? -- Part 2. Single celled organisms -- Experimental evolution of microbial host-parasite relations -- Engineering microbial communities that evolve in a spatial setting -- Sharing is caring: differential gene flow in microbial communities.-Synthetic biology to study the evolution of gene regulatory networks -- Evolution of stem cell differentiation -- The evolution of epigenetic switches and cellular clocks -- Part 3. Multicellular organisms -- Measuring the genotype-phenotype map in eukaryotes -- Pigment evolution in Drosophila fly species: time for theory? -- Birds of a feather: using experiment and theory to understand the evolution of feather patterning -- A regulatory network that explains both fish fins and mouse limbs -- Quantitative system drift of the fly body plan -- Part 4. Immunity and disease -- Of mice, men, and immunity -- Immunity as an evolving adaptive system -- Cancer is a microevolutionary systemic disease -- A systems approach to cancer.
520	3		_aThis new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and better analysis and modeling techniques that will open new avenues of scientific inquiry.
988			_aSpringer_Computer_2021
650		7	_2embne _aBioinformática _9160489
650		7	_2embne _aEvolución _9138470
700	1		_aCrombach, Anton _eeditor literario
776	0	8	_iPrinted edition: _z9783030717360
776	0	8	_iPrinted edition: _z9783030717384
776	0	8	_iPrinted edition: _z9783030717391
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-71737-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _eu _zSI