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008			211123s2021 si | o |||| 0|eng d
020			_a9789811654855
024	7		_a10.1007/978-981-16-5485-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQD78 _b2021 EB
100	1		_aWan, Qian-Hong _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9680666
245	1	0	_aMixed-Mode Chromatography : _bPrinciples, Methods, and Applications _cby Qian-Hong Wan
250			_aFirst edition 2021
264		1	_aSingapore _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XIII, 482 páginas) _b216 ilustraciones, 65 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_aChapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing. .
520	3		_aThe book is about the technology and application of Mixed-mode chromatography (MMC). Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology. .
988			_aSpringer_BiomedLife_2021
650		7	_2embne _9540627 _aQuímica analítica
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-16-5485-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2022 _dz _eb _zSI