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008			211118s2021 si | o |||| 0|eng d
020			_a9789811614989
024	7		_a10.1007/978-981-16-1498-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRK341 _b2021 EB
245	0	0	_aCoal-burning Type of Endemic Fluorosis : _bPathophysiology and Clinical Treatments _cedited by Zhi-Zhong Guan
250			_aFirst edition 2021
264		1	_aSingapore _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XVI, 465 páginas) _b23 ilustraciones, 19 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_aChapter 1. Discovery and Concept of Endemic Fluorosis -- Chapter 2. Epidemic Status of Coal-burning Type of Endemic Fluorosis -- Chapter 3. Skeletal Fluorosis -- Chapter 4. Medical Imaging Manifestation of Skeletal Fluorosis -- Chapter 5. Epidemic characteristic and pathogenesis of dental fluorosis -- Chapter 6. Damage in Nervous System -- Chapter 7. Modification of Digestive System -- Chapter 8. Modification of Urinary System -- Chapter 9. Modification of Cardio-Vascular System -- Chapter 10.Damage of Endocrine System -- Chapter 11. Damages to Reproductive System by Coal-burning Type of Endemic Fluorosis -- Chapter 12. Enhanced Oxidative Stress -- Chapter 13. High Level of Inflammation -- Chapter 14. Effect of Fluoride on Signal Transduction Pathways -- Chapter 15. Changes of Receptors -- Chapter 16. Alteration of Endoplasmic Reticulum Stress -- Chapter 17. Mitochondrial Changes -- Chapter 18. Calcium Metabolism Disorder in Chronic fluorosis -- Chapter 19. Altering of Carbohydrate Metabolism -- Chapter 20. Changes in Gene Expression -- Chapter 21. Biological Indicators for Early Diagnosis of Endemic Fluorosis -- Chapter 22. Comprehensive Prevention and Control of Coal-burning Type of Endemic Fluorosis -- Chapter 23. Surgical Treatment of Joint Damage in Skeletal Fluorosis -- Chapter 24. Clinical Treatment of Dental Fluorosis -- Chapter 25. Drug Development -- Chapter 26. Improvement of Health Condition of the Residents in the Areas of Coal-burning Type of Endemic Fluorosis after Comprehensive Treatments.
520	3		_aEndemic fluorosis is caused by excessive intake of fluorine in drinking water, air, food, tea and other media in a specific natural environment for a long time, which involves at least 25 countries, such as China, India, Vietnam, Iran, Egypt, Mexico, Argentina and influences more than 200 million of population. China and India are the countries with the most extensive endemic fluorosis and the most serious damages. There are three main intake sources of endemic fluorosis, e.g., drinking water, coal-burning pollution and drinking tea. Coal-burning type of endemic fluorosis was established in Guizhou Province of China in 1970's. The residents in the areas used indoor stoves with no flue to burn coals with high content of fluoride to bake grains in the autumn and heat in the winter. This results in excessive intake of fluorine and then leads chronic poisoning. It has been confirmed that 13 provinces of China with 34.3 million of population are influenced by this type of fluorosis with severe injuries to most organs of human body. The content of this book covers the epidemiology, pathological changes, molecular pathogenesis and clinical treatments of the disease. This book is a suitable reference for the researchers and graduate students in this field, which is helpful to improve the understanding of this disease and to take preventive measures.
988			_aSpringer_BiomedLife_2021
650		7	_2embne _9168892 _aDientes _xEnfermedades
650		7	_2embne _9294206 _aAgua _xControl de calidad
700	1		_aGuan, Zhi-Zhong _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9680672
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-16-1498-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2022 _dz _eb _zSI