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020			_a9783030811471
024	7		_a10.1007/978-3-030-81147-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC343 _b2021 EB
245	0	0	_aCircadian Clock in Brain Health and Disease _cedited by Olivia Engmann, Marco Brancaccio
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XI, 188 páginas) _b15 ilustraciones, 13 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aAdvances in Experimental Medicine and Biology _x2214-8019 _v1344
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_aPART I. Molecular Gears of the Circadian Clock -- Introduction to the Clock System -- Circadian Clocks, Sleep, and Metabolism -- Linking Depression to Epigenetics: Role of the Circadian Clock -- PART II. Brain Regions Implicated in Circadian Rhythms -- The Brain's Reward System in Health and Disease -- Brain Clocks, Sleep and Mood -- Astrocyte Circadian Timekeeping in Brain Health and Neurodegeneration -- PART III. Clock and Mental Illness -- The Role of the Circadian System in Attention Deficit Hyperactivity Disorder -- How Psychoactive Drugs and the Circadian Clock Are Enlightening One Another -- Circadian Rhythms in Mood Disorders -- The Reciprocal Interaction Between Sleep and Alzheimer's Disease.
520	3		_aIn this book, leading experts in the field review how circadian rhythms impact the brain. An essential function of mammalian life is the exploitation of the regularities provided by the 24-hour cycle of day and night. The development and evolution of circadian clock mechanisms have allowed us to optimally adapt our behavior and physiology to the external world. Not surprisingly, a growing body of evidence links the disruption of circadian rhythms by genetic, lifestyle and environmental factors to illnesses of the brain. In the first section of the book, readers will learn about the molecular and anatomic architecture of circadian function in mammals. The ways in which environmental disruptions and misalignments can influence such mechanisms and therefore impair brain function and health status are also addressed. In the second part, the focus shifts to those brain regions responsible for brain function and the body-wide regulation of circadian function. Amongst others, special attention is paid to the role of astrocytes and the brain's reward and hyprocretin / orexin systems. The book concludes with an extensive discussion on the consequences of circadian rhythm dysfunction. Several chapters present the latest findings on Attention Deficit Hyperactivity Disorder, schizophrenia, autism spectrum disorder, drug abuse and mood disorders. Written by auhorities in the field, the book provides a state-of-the-art review of the latest findings on circadian clocks in the brain and highlights their potentially far-reaching impacts on our health and well-being. As such, it is essential reading for all neuroscientists and clinicians seeking to understand the intricate connections between circadian rhythms and brain health and illness.
988			_aSpringer_BiomedLife_2021
650		7	_2embne _aNeurociencias _9158907
650		7	_2embne _9141010 _aNeuropsicología
700	1		_aEngmann, Olivia _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9680733
700	1		_aBrancaccio, Marco _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _9680734
776	0	8	_iPrinted edition: _z9783030811464
776	0	8	_iPrinted edition: _z9783030811488
776	0	8	_iPrinted edition: _z9783030811495
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-81147-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2022 _dz _eb _zSI