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020 _a9783030676964
024 7 _a10.1007/978-3-030-67696-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH582.4
_b2021 EB
245 0 0 _aCellular Biology of the Endoplasmic Reticulum
_cedited by Luis B. Agellon, Marek Michalak
250 _aFirst edition 2021
264 1 _aCham
_bSpringer International Publishing
_c2021
300 _a1 recurso en línea (VIII, 327 páginas)
_b27 ilustraciones, 22 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aProgress in Molecular and Subcellular Biology
_x2197-8484
_v59
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aA View of the Endoplasmic Reticulum Through the Calreticulin Lens -- Structural Analysis of Calreticulin, an Endoplasmic Reticulum-Resident Molecular Chaperone -- The Role of Endoplasmic Reticulum Chaperones in Protein Folding and Quality Control -- Proteins Interacting with STIM1 and Store-Operated Ca2+ Entry -- Endoplasmic Reticulum (ER) and ER-Phagy -- Defects in Protein Folding and/or Quality Control Cause Protein Aggregation in the Endoplasmic Reticulum -- Roles of Calreticulin in Protein Folding, Immunity, Calcium Signaling and Cell Transformation -- Impact of Calreticulin and Its Mutants on Endoplasmic Reticulum Function in Health and Disease -- Cancer Biology of the Endoplasmic Reticulum Lectin Chaperones Calreticulin, Calnexin and PDIA3/ERp57 -- Maintenance of Endoplasmic Reticulum Protein Homeostasis in Cancer: Friend or Foe -- IP3 Receptor Biology and Endoplasmic Reticulum Calcium Dynamics in Cancer -- Disruption of Endoplasmic Reticulum Proteostasis in Age-Related Nervous System Disorders -- Endoplasmic Reticulum Homeostasis and Stress Responses in Caenorhabditis elegans -- Tardigrada: An Emerging Animal Model to Study the Endoplasmic Reticulum Stress Response to Environmental Extremes. .
520 3 _aThis book provides a comprehensive overview of the biology of the endoplasmic reticulum (ER) and the associated ER proteins, it discusses their structure, function and signaling mechanisms in the cell and their role in disease. This book also offers insights into the practical aspects of research and demonstrates the use of non-mammalian models to study the structure and function of the ER. Written by leading experts in the field, the book enables readers to gain a thorough understanding of current ER biology. It is intended for scientists and clinical researchers working on the endoplasmic reticulum in all its various roles and facets in health and disease. .
988 _aSpringer_BiomedLife_2021
650 7 _2embne
_aCélulas
_9139475
650 7 _2embne
_aBiología molecular
_9139103
700 1 _aAgellon, Luis B.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMichalak, Marek.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030676957
776 0 8 _iPrinted edition:
_z9783030676971
776 0 8 _iPrinted edition:
_z9783030676988
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-67696-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b01/2022
_dz
_eb
_zSI