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020			_a9783030675929
024	7		_a10.1007/978-3-030-67592-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP551 _b2021 EB
245	0	4	_aThe Collagen Superfamily and Collagenopathies _cedited by Florence Ruggiero
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (IX, 338 páginas) _b28 ilustraciones, 24 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiology of Extracellular Matrix _x2191-1959 _v8
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_aChapter 1: Introduction to the collagen superfamily -- Chapter 2: Collagen IV-related disease -- Chapter 3: Articular collagens related diseases -- Chapter 4: Collagens as new players of nervous system disease -- Chapter 5: Collagens and EDS -- Chapter 6: Collagens and dystrophic epidermolysis bullosa -- Chapter 7: Collagen-related myopathies: pathogenic mechanisms and prospective therapies -- Chapter 8: Procollagen trafficking and its implicaitons in Osteogenesis Imperfecta.
520	3		_aThis book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling events and serve critical regulatory roles in various cell functions during embryonic development and adult homeostasis. Furthermore, collagens are associated with a broad spectrum of heritability-related diseases known as "collagenopathies" that affect a multitude of organs and tissues including sensorial organs. The book is a useful introduction to the field for junior scientists, interested in extracellular matrix research. It is also an interesting read for advanced scientists and clinicians working on collagens and collagenopathies, giving them a broader view of the field beyond their area of specialization.
988			_aSpringer_BiomedLife_2021
650		7	_2embne _aProteínas _9139861
700	1		_aRuggiero, Florence. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030675912
776	0	8	_iPrinted edition: _z9783030675936
776	0	8	_iPrinted edition: _z9783030675943
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-67592-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2022 _dz _eb _zSI