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020 _a9789813366992
024 7 _a10.1007/978-981-33-6699-2
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC268.4
_b2021 EB
245 0 0 _aGenetic Polymorphism and cancer susceptibility
_cedited by Aga Syed Sameer, Mujeeb Zafar Banday, Saniya Nissar
250 _aFirst edition 2021
264 1 _aSingapore
_bSpringer International Publishing
_c2021
300 _a1 recurso en línea (XXI, 339 páginas)
_b48 ilustraciones, 46 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aChapter 1. Polymorphisms and Mutation: What is difference? -- Chapter 2. Single nucleotide polymorphisms and pharmacogenomics -- Chapter 3. Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility -- Chapter 4. From inflammation to cancer: Role of genetic polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer -- Chapter 5. Colorectal Cancer and genetic polymorphism in key regulatory low penetrance genes -- Chapter 6. Role of Genetic Polymorphisms in Breast Cancer -- Chapter 7. Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer -- Chapter 8. Thyroid Cancer and genetic polymorphism -- Chapter 9. SNPs of TLRs and Bladder Cancer -- Chapter 10. Role of genetic polymorphisms in Lung Cancer.
520 3 _aThis book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.
988 _aSpringer_BiomedLife_2021
650 7 _2embne
_9273952
_aCáncer
_xAspectos genéticos
700 1 _aSameer, Aga Syed.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aBanday, Mujeeb Zafar.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aNissar, Saniya.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9789813366985
776 0 8 _iPrinted edition:
_z9789813367005
776 0 8 _iPrinted edition:
_z9789813367012
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-33-6699-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2022
_dz
_eb
_zSI