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008			210421s2021 sz | o |||| 0|eng d
020			_a9783030442118
024	7		_a10.1007/978-3-030-44211-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aR857.T55 _b2021 EB
245	0	0	_aOrgan Tissue Engineering _cedited by Daniel Eberli, Sang Jin Lee, Andreas Traweger
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea _b61 ilustraciones, 55 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aTissue Engineering and Regeneration _x 2731-0566
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aReference Module Biomedical and Life Sciences (SpringerNature-43744)
505	0		_aBrain Central Neural System -- Vison system, retina, cornea -- Olfactory system -- Craniomaxillofacial bone engineering -- Ear, Nose and Throat -- Dental, tooth -- Thymus, Lymphoid -- Oesophagus, Trachea -- Lung -- Gastro Intestinal Tract (Organoids) -- Kidney -- Bladder/Urethra -- Liver (Biomaterial, Cells) -- Endocrine Organs (Pancreas) -- Salivary grand -- Breast Tissue / Fat Tissue -- Ovary -- Penis -- Great Vessels -- Cell sheets for cardiac tissue engineering -- Heart valve Bioengineering -- Ligament -- Meniskus als muskuloskelettaler Abschnitt -- Tendons -- Skeletal system and Muscle.
520	3		_aThe notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.
988			_aSpringer_BiomedLife_2021
650		7	_2embne _9678347 _aMedicina regenerativa
650		7	_2embne _9143820 _aIngeniería biomédica
700	1		_aEberli, Daniel. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLee, Sang Jin. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aTraweger, Andreas. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030442101
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-44211-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _eb _zSI