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020 _a9783030660147
024 7 _a10.1007/978-3-030-66014-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRE661.D3
_b2021 EB
245 0 0 _aAge-related Macular Degeneration :
_bFrom Clinic to Genes and Back to Patient Management
_cedited by Emily Y. Chew, Anand Swaroop
250 _aFirst edition 2021
264 1 _aCham
_bSpringer International Publishing
_c2021
300 _a1 recurso en línea (X, 314 páginas)
_b73 ilustraciones, 61 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aAdvances in Experimental Medicine and Biology
_x2214-8019
_v1256
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _a1. Age-Related Macular Degeneration: Epidemiology and Clinical Aspects -- 2. Ocular Imaging for Enhancing the Understanding, Assessment, and Management of Age-Related Macular Degeneration -- 3. Histopathology of Age-Related Macular Degeneration and Implications for Pathogenesis and Therapy -- 4. Bruch's Membrane and the Choroid in Age-Related Macular Degeneration -- 5. Innate Immunity in Age-Related Macular Degeneration -- 6. Immunological Aspects of Age-Related Macular Degeneration -- 7. AMD Genetics: Methods and Analyses for Association, Progression, and Prediction -- 8. Making Biological Sense of Genetic Studies of Age-Related Macular Degeneration -- Age-Related Macular Degeneration: From Epigenetics to Therapeutic Implications -- 10. Mitochondria: The Retina's Achilles' Heel in AMD -- 11. Cell-Based Therapies for Age-Related Macular Degeneration -- 12. Current Management of Age-Related Macular Degeneration.
520 3 _aThis edited book focuses on the recent advances in our understanding of age-related macular degeneration (AMD), combining epidemiology and clinical diagnosis, with genetics and immunological aspects as well as the role of proteostasis and mitochondria before diving into new therapies including stem cell based approaches. AMD is a leading cause of largely incurable blindness worldwide and projected to double from 2.07 million to 5.44 million individuals by 2050 in the United States. Globally, 288 million individuals are projected to have AMD by 2040. The disease has enormous socioeconomic impact on the affected individuals, their families and the society. This book will bring together the state of the art basic science knowledge with clinically relevant findings and address the challenges for future research in AMD. The intersection of different disciplines will provide potential areas for further investigations to reduce the burden of blindness from AMD. This book offers an appealing and insightful resource for clinicians, scientists, students and fellows.
988 _aSpringer_BiomedLife_2021
650 7 _2embne
_9670079
_aDegeneración macular
700 1 _aChew, Emily Y.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSwaroop, Anand.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030660130
776 0 8 _iPrinted edition:
_z9783030660154
776 0 8 _iPrinted edition:
_z9783030660161
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-66014-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2022
_dz
_eb
_zSI