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008			210913s2021 sz | o |||| 0|eng d
020			_a9783030855369
024	7		_a10.1007/978-3-030-85536-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP111.4 _b2021 EB
100	1		_aKartha, C. Chandrasekharan _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9681489
245	1	0	_aCardiomyocytes in Health and Disease _cby Chandrasekharan C. Kartha
250			_aFirst edition 2021
264		1	_aCham _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XXVII, 345 páginas) _b44 ilustraciones, 43 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_aSection I: Normal Cardiomyocyte and its Growth -- 1. Structure and Function of Cardiomyocyte -- 2. Development of Cardiomyocyte -- 3. Cell Cycle Regulation in Cardiomyocytes -- 4. Cardiac Fibroblast and Cardiomyocyte Growth -- 5. Role of Endocardium and Epicardium in Generation of Cardiomyocytes -- Cardiomyocytes in the Mammalian Adult Heart -- 7. Energy Metabolism in Cardiomyocytes -- Section II: Cardiomyocyte Responses 8. Response of Cardiomyocytes to Mechanical Stress -- Cardiomyocyte Responses to Hormones 10. Sequelae of Genetic Defects in Cardiomyocytes -- 11. Response and Effects of Cardiomyocyte Progenitors in the Infarcted Heart -- Section III: Cardiomyocyte Aging and Death -- 12. Cardiomyocyte Senescence -- 13. Mechanisms of Cardiomyocyte Death -- 14. Cardiomyocyte Response to Ischemic Injury -- 15. Cardiomyocytes in Heart Failure -- Section IV: Cardiomyocyte Regeneration -- 16. Endogenous Mechanisms for Cardiomyocyte Regeneration -- 17. Mechanisms to Induce Cardiomyocyte Proliferation -- 18. Cell Sources of Cardiomyocytes for Heart Repair -- 19. Reprograming Fibroblasts for Cardiomyocytes and Progenitors -- Section V: Translational Aspects of Cardiomyocyte Biology -- 20. Clinical Translation of Discoveries in Cardiomyocyte Biology.
520	3		_aThis book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon. .
988			_aSpringer_BiomedLife_2021
650		7	_2embne _9138127 _aCorazón _xFisiología
650		7	_2embne _9678347 _aMedicina regenerativa
776	0	8	_iPrinted edition: _z9783030855352
776	0	8	_iPrinted edition: _z9783030855376
776	0	8	_iPrinted edition: _z9783030855383
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-85536-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2022 _dz _eb _zSI