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020 _a9783030702700
024 7 _a10.1007/978-3-030-70270-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC591
_b2021 EB
100 1 _aRayees, Sheikh
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9681316
245 1 0 _aAsthma :
_bPathophysiology, Herbal and Modern Therapeutic Interventions
_cby Sheikh Rayees, Inshah Din
250 _aFirst edition 2021
264 1 _aCham
_bSpringer International Publishing
_c2021
264 4 _c2021
300 _a1 recurso en línea (IX, 69 páginas)
_bilustraciones
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aArchivo de texto
_bPDF
490 0 _aSpringerBriefs in Immunology
_x2194-2781
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aAsthma -- Pathophysiology asthma -- Airway inflammation and airway hyperresponsiveness -- Effects of inflammation -- Inflammatory cells involved in asthma -- Transcription factors involved in Th2 cell differentiation -- Current asthma treatments -- Cytokine-based therapies -- Transcription factor modulators -- Preclinical mouse models of asthma used to evaluate drug efficacy and properties and associated drawbacks -- Herbal treatments of asthma -- Traditional plants with anti-asthmatic potential -- Asthma Chinese Herbal Remedies -- Future potential of herbal-based medicinal treatment for management of asthma.
520 3 _aAsthma is a chronic airway disease affecting over 300 million people worldwide with an expected increase of an additional 100 million by 2025. Past decade has observed a notable increase in asthma prevalence on both national and global levels with highest rates observed in western countries (about 30%). Over the past 40 years, a drastic increase in global prevalence, morbidity, mortality, and economic burden have been observed due to asthma especially in children. The rising numbers of hospital admissions for asthma, especially young children, reflect an increase in severe asthma, poverty and lack of proper disease management. Worldwide, approximately 180,000 deaths annually are caused due to this condition. The financial burden on a single asthma patient per year in different western countries ranges from US$300-1,300. Asthma is an intricate respiratory disorder with differences in its severity, natural history and hence treatment response. These differences in intensities of various presentations such as bronchial hyper-responsiveness, airway inflammation, mucus production, airflow obstruction make asthma a heterogeneous disease. The mainstay of current therapies for asthma includes inhaled corticosteroids, phosphodiesterase inhibitors, leukotriene modifiers and β2-adrenoceptor agonists. Some of the currently available drugs are efficient in one or more aspects. However the associated side effects or heterogeneity of the disease limit their usefulness and efficacy, thereby putting a demand on development of new drugs and therapies. On the other hand, asthma has also been treated/managed via herbal medications. These approaches have been described in Unani, Ayurvedic or Chinese system of medicine since antiquity. In fact, several anti-asthmatic drugs were developed from herbs commonly utilized in the non-Western system of medicine. This book focuses on the pathophysiology of asthma, its medication (both herbal and modern), limitations and their future prospects.
988 _aSpringer_BiomedLife_2021
650 7 _2embne
_9140908
_aAsma
700 1 _aDin, Inshah
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9681317
776 0 8 _iPrinted edition:
_z9783030702694
776 0 8 _iPrinted edition:
_z9783030702717
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-70270-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
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998 _b01/2022
_dz
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_zSI