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| 020 | _a9783030688448 | ||
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_a10.1007/978-3-030-68844-8 _2doi |
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_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC |
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_aQP623 _b2021 EB |
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| 100 | 1 |
_aHolvoet, Paul _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9681315 |
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| 245 | 1 | 0 |
_aNon-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer _cby Paul Holvoet |
| 250 | _aFirst edition 2021 | ||
| 264 | 1 |
_aCham _bSpringer International Publishing _c2021 |
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| 264 | 4 | _c2021 | |
| 300 |
_a1 recurso en línea (XXX, 265 páginas) _b26 ilustraciones |
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| 336 |
_2rdacontent _aTexto _btxt |
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| 337 |
_2rdamedia _aelectrónico _bc |
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| 338 |
_2rdacarrier _arecurso electrónico _bcr |
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| 347 |
_aArchivo de texto _bPDF |
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| 490 | 0 | _aBiomedical and Life Sciences (SpringerNature-11642) | |
| 490 | 0 | _aBiomedical and Life Sciences (R0) (SpringerNature-43708) | |
| 505 | 0 | _aBiogenesis and Modes of Action Of miRs And Circular And Long Non-coding RNAs -- Obesity, Insulin Resistance in Adipose Tissue And Thermogenesis -- Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease -- Atherosclerosis -- Cardiomyopathy and Heart Failure -- Cancer -- Communication between Tumor-Adjacent Tissues and Tumors with Emphasis on Role of Inflammatory Cells -- General Conclusions and Future Perspectives. | |
| 520 | 3 | _aThis book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a cluster of non-coding RNAs that may be prospectively analyzed in extensive cohort studies to determine their value in risk-predicting machine learning algorithms. In addition, it emphasizes the role of microvesicles in communication between tumor-adjacent tissue, inflammatory cells, and tumor cells, with a special focus on the role of miR-155. The book intends to promote interdisciplinary research. Due to the comprehensive background information provided in each chapter, it is suitable for researchers in academia and industry and for graduate students in biology, bioengineering, and medicine. . | |
| 988 | _aSpringer_BiomedLife_2021 | ||
| 650 | 7 |
_2embne _9140525 _aÁcidos nucleicos |
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| 776 | 0 | 8 |
_iPrinted edition: _z9783030688431 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783030688455 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783030688462 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-68844-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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_b01/2022 _dz _ek _zSI |
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