000			02838nam a22003735i 4500
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
988			_aSpringer_Medicine_2018
999			_c343877 _d343877 _x1
001			343877
003			ES-MaUEC
005			20230102120150.0
006			a||||fo|||| 00| 0
007			cr nn nnnaamaa
008			180926s2018 gw | s |||| 0|eng d
020			_a9783319945712
024	7		_a10.1007/978-3-319-94571-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aRB155.5 _b2018 EB
245	1	0	_aAlagille Syndrome : _bPathogenesis and Clinical Management _cedited by Binita M. Kamath, Kathleen M. Loomes.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XIV, 198 páginas) _b41 ilustraciones, 31 ilustraciones a color
490			_aMedicine (Springer-11650)
505	0		_aThe Alagille Syndrome: Overview and Introduction -- Bile Duct Development and the Notch Signaling Pathway -- Genetics of Alagille Syndrome -- Liver Disease in Alagille Syndrome -- Transplant Considerations in Alagille Syndrome -- Cardiac, Aortic, and Pulmonary Vascular Involvement in Alagille Syndrome -- Vascular Manifestations in Alagille Syndrome -- The Renal Sequelae of Alagille Syndrome as a Product of Altered Notch Signaling During Kidney Development -- Skeletal Involvement in Alagille Syndrome -- Immune Dysregulation in Alagille Syndrome: A Feature of the Evolving Phenotype -- Health-Related Quality of Life and Neurocognition in Alagille Syndrome -- Future Therapeutic Approaches for Alagille Syndrome.
520			_aThis text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and strategies. The text also touches upon future treatment options. Written by experts in the field, Alagille Syndrome: Pathogenesis and Clinical Management is a valuable resource for physicians and researchers dealing with this disorder, one that will help guide patient management and stimulate investigative efforts.
650		7	_2embne _aCromosomas _9139992
700	1		_aKamath, Binita M. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLoomes, Kathleen M. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783319945705
776	0	8	_iPrinted edition: _z9783319945729
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-94571-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _a_alco _a_vill _b02/2019 _cm _dz _feng _ggw _h0