000 04116nam a22003615i 4500
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
988 _aSpringer_Medicine_2018
999 _c343854
_d343854
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020 _a9783319905785
024 7 _a10.1007/978-3-319-90578-5
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aRC862.I53
_b2018 EB
245 1 0 _aFibrostenotic Inflammatory Bowel Disease
_cedited by Florian Rieder.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XII, 397 páginas)
_b70 ilustraciones, 67 ilustraciones a color
490 _aMedicine (Springer-11650)
505 0 _aFibrostenotic Inflammatory Bowel Disease - a Cinderella story -- Epidemiology and Natural History of Fibrostenosing Inflammatory Bowel Disease -- Genetic influences on the development of fibrosis in inflammatory bowel disease -- Epigenetic regulation of intestinal fibrosis -- Cytokine and Anti-cytokine Agents as Future Therapeutics for Fibrostenosing IBD -- Inflammation-independent mechanisms of intestinal fibrosis: the role of the extracellular matrix -- Fat and Fibrosis -- Environmental factors and their influence on intestinal fibrosis -- Animal models and sources of mesenchymal cells in intestinal fibrosis -- Fibrosis in Ulcerative Colitis -- Histopathology of intestinal fibrosis -- Clinical, Cellular and Serologic Biomarkers of intestinal fibrosis -- The future of intestinal fibrosis imaging -- Imaging in intestinal fibrosis. What is state of the art? -- Medical therapy of stricturing IBD -- Endoscopic therapy of intestinal strictures - What is state of the art? -- Resectional surgery for intestinal strictures - What is state of the art? -- Management of ileal pouch strictures and anal stricturing disease - A clinical challenge -- The future of surgical therapy of stricturing IBD -- Challenges of translation of anti-fibrotic therapies into clinical practice in IBD -- What distinguishes mechanisms of fistula and stricture formation -- The Pathogenesis of Intraabdominal Adhesions:Similarities and Differences to Luminal Fibrosis -- Anti-fibrotic therapies from other organs - What the gut can learn from the liver, skin, lung and heart. .
520 _aThis book provides a comprehensive account of the pathogenesis and treatment of intestinal fibrosis, covering both the clinical and molecular aspects of the disease. It begins by describing the epidemiology and genetics of fibrostenosing IBD in Crohn's disease and Ulcerative colitis as well as the epigenetics and cellular and molecular mechanisms of the disease. Readers will obtain an in-depth overview of the disease from biomarkers and histology to surgical intervention, imaging and current and future drug therapies. Medical management of fibrosis, endoscopy and imaging as well as surgical approaches are all discussed. Through the links to videos contained in the book, the reader will become familiar with interventional procedures such as endoscopic balloon dilation and surgical techniques for stricturing IBD, such as resection and strictureplasties. This is an indispensable volume for anyone working on fibrostenotic IBD, such as gastroenterologists, internists, radiologists, colorectal surgeons, pathologists and researchers. It has been written by a team of top experts from North America, Asia and Europe.
650 7 _2embne
_9185357
_aIntestinos
_xEnfermedades
700 1 _aRieder, Florian.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783319905778
776 0 8 _iPrinted edition:
_z9783319905792
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-90578-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_a_alco
_a_vill
_b02/2019
_cm
_dz
_feng
_ggw
_h0