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008			210217s2021 gw | s |||| 0|eng d
020			_a9783030640095
024	7		_a10.1007/978-3-030-64009-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _erda _dES-MaUEC
050		4	_aRL110 _b2021 EB
245	0	0	_aNew Therapies in Advanced Cutaneous Malignancies _cedited by Piotr Rutkowski, Mario Mandalà
250			_aFirst edition 2021
264		1	_aCham, Switzerland _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XIV, 457 páginas) _b28 ilustraciones, 25 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
505	0		_aPart 1. Pathological, molecular and immunological background of Cutaneous Malignancies -- Pathology of Melanoma and Skin Carcinomas -- Molecular Landscape Profile of Melanoma -- Molecular Landscape of Skin Carcinomas -- Immunological Features of Melanoma -- Part 2. Targeted Therapies in Skin Cancers -- Dabrafenib and Trametinib -- Vemurafenib and Cobimetinib -- Encorafenib and Binimetinib -- Vismodegib -- Sonidegib -- Part 3. Immunological Strategies in Advanced Melanoma -- Ipilimumab -- Nivolumab -- Pembrolizumab -- Talimogene Leharparepvec -- Part 4. Future of Melanoma Immunotherapy -- Perspectives of Immunotherapy in Advanced Melanoma Combinations and Sequencing -- Part 5. Immunological Therapies in Advanced Skin Carcinomas -- Avelumab -- Cemiplimab -- Perspectives of Immunotherapy in Non-Melanoma Skin Cancers -- Part 6. Mechanism of Resistance to Therapy -- Mechanisms of Resistance to Targeted Therapies in Skin Cancer -- Mechanisms of Resistance to Immunotherapy -- Part 7. Perioperative Therapy of Melanoma -- Neoadjuvant and Adjuvant Therapy in Melanoma -- Part 8. Special Techniques and Populations -- Adoptive Cell Therapy Immunological Therapies in Special Populations: HIV, Hepatitis and Organ Transplantation -- Conclusions.
520	3		_aThis book provides a detailed overview of the activity and efficacy of new treatments and promising perspectives in the field of cutaneous malignancies. The first part of the book covers the basic molecular and immunological mechanisms. It then goes on to cover specific strategies in melanoma and non-melanoma skin cancers that, starting from the basic mechanisms, translate this information into clinical routine or translational research. This unique handbook comprises very practical structured descriptions of more than 10 new agents used in treatment of melanomas and skin carcinomas together with biological background of their mechanisms of action. It provides structured and up-to-date information about all therapeutics in cutaneous malignancies, making it extremely useful in clinical practice, for clinicians that need timely and focused information. Prepared by a group of international authors from expert melanoma centres in Europe, the book provides knowledge distilled from the diverse perspectives of the contributing authors (pathologists, translational scientists and clinicians). This book is of interest to medical oncologists, oncological surgeons, dermatologists and immunologists as well as biologists and pharmacologists.
988			_aSpringer_Medicine_2021
650		7	_2embne _9176385 _aPiel _xEnfermedades _xTratamiento
650		7	_2embne _9205316 _aPiel _xCáncer
700	1		_aRutkowski, Piotr _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aMandalà, Mario _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030640088
776	0	8	_iPrinted edition: _z9783030640101
776	0	8	_iPrinted edition: _z9783030640118
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-64009-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2021 _dz _ea _zSI