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020			_a9789813347991
024	7		_a10.1007/978-981-33-4799-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _erda _dES-MaUEC
050		4	_aRC633 _b2021 EB
100	1		_aBhargava, Manorama _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9678297
245	1	0	_aHematologic Malignancies . _bCase Studies in Cytogenetic and Molecular Genetics _cby Manorama Bhargava.
250			_aFirst edition 2021
264		1	_aSingapore _bSpringer International Publishing _c2021
300			_a1 recurso en línea (XXVI, 246 páginas) _b232 ilustraciones, 114 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aArchivo de texto _bPDF
505	0		_aTechniques in Cytogenetics -- Techniques in Molecular Haematology -- Part: I - Case Studies in Myeloid Malignancies -- Acute Myeloid Leukemia -- Myelodysplastic Syndrome -- Myelodysplastic Syndromes - Myeloproliferative Neoplasms -- Myeloproliferative Neoplasms -- Chronic Myeloid Leukemia -- Next Generation Sequencing for Diagnostics of Myeloid Malignancies for Routine Clinical Use: Pitfalls and Advantages -- Part: II - Case Studies in Lymphoid Malignancies -- Acute Lymphoblastic Leukemia -- Chronic Lymphocytic Leukemia and Non Hodgkin's Lymphoma -- Part: III - Case Studies in Multiple Myeloma -- Multiple Myeloma.
520	3		_aThis book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.
988			_aSpringer_Medicine_2021
650		7	_2embne _9169169 _aSangre _xEnfermedades _xAspectos genéticos
650		7	_2embne _aLeucemia _xAspectos genéticos _9140673
650		7	_2embne _9519857 _aMédula ósea _xEnfermedades _xAspectos genéticos
776	0	8	_iPrinted edition: _z9789813347984
776	0	8	_iPrinted edition: _z9789813348004
776	0	8	_iPrinted edition: _z9789813348011
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-33-4799-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2021 _dz _ea _zSI