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020 _a9789813363144
024 7 _a10.1007/978-981-33-6314-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_erda
_dES-MaUEC
050 4 _aRC267
_b2021 EB
100 1 _aWani, Mohmmad Younus
_eautor
_4http://id.loc.gov/vocabulary/relators/aut
_9678207
245 1 0 _aGold and its Complexes in Anticancer Chemotherapy
_cby Mohmmad Younus Wani, Manzoor Ahmad Malik.
250 _aFirst edition 2021
264 1 _aSingapore
_bSpringer Singapore
_c2021
300 _a1 recurso en línea (IX, 173 páginas)
_b124 ilustraciones, 29 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aarchivo de trexto
_bPDF
_2rda
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aChapter 1. Cancer -- Chapter 2. Types of cancer -- Chapter 3. Classification -- Chapter 4. Cancer or tumor nomenclature -- Chapter 5. Heterogeneity -- Chapter 6. Invasion and metastasis -- Chapter 7. How cancer arises? -- Chapter 8. Epidemiology -- Chapter 9. Economic burden -- Chapter 10. Treatment modalities -- Chapter 11. Chemotherapy -- Chapter 12. Properties of metals and metal complexes -- Chapter 13. Platinum based anticancer agents -- Chapter 14. Chemistry of cisplatin -- Chapter 15. Mechanism of action of platinum drugs -- Chapter 16. Non-platinum anticancer agents -- Chapter 17. Chemistry of gold -- Chapter 18. Gold and its complexes in medicine -- Chapter 19. Auranofin and its analogues -- Chapter 20. Classes of gold complexes -- Chapter 21. Mechanisms of action of anticancer gold complexes -- Chapter 22. Perspectives.
520 3 _aThis book presents an overview of cancer and the genesis, and development of different treatment strategies and modalities against cancer. The emergence of gold and its complexes as promising anticancer chemotherapeutic agents have the potential to substitute or replace the platinum based chemotherapeutic agents. Gold complexes have demonstrated considerable anti-proliferative properties, chiefly attributed to their anti-mitochondrial effects, they make gold complexes excellent candidates as anti-cancer agents compared to their platinum-based counterparts. This book provides a critical review of recent advances made in the development of gold complexes as anti-cancer agents. In this context, it examines a number of different ligand architectures, provides comprehensive information on gold complexes' mechanism of action and toxicity issues and, in closing, outlines future research directions.
988 _aSpringer_BiomedLife_2021
650 7 _2embne
_aCáncer
_xInvestigación
_9182523
650 7 _2embne
_9405304
_aAntineoplásicos
700 1 _aMalik, Manzoor Ahmad
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9678208
776 0 8 _iPrinted edition:
_z9789813363137
776 0 8 _iPrinted edition:
_z9789813363151
776 0 8 _iPrinted edition:
_z9789813363168
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-33-6314-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
_n0
998 _b04/2021
_dz
_ek
_zSI