000 03863nam a22004575i 4500
006 a||||fo|||| 00| 0
007 cr nn nnnaamaa
999 _c329593
_d329593
_x1
001 329593
003 ES-MaUEC
005 20230102114426.0
008 201215s2020 gw | s |||| 0|eng d
020 _a9783030583309
024 7 _a10.1007/978-3-030-58330-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP88.23
_b2020 EB
245 0 0 _aExtracellular Matrix Omics
_cedited by Sylvie Ricard-Blum
250 _aFirst edition 2020
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2020.
300 _a1 recurso en línea (VIII, 225 páginas)
_b22 ilustraciones, 20 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiology of Extracellular Matrix
_x0887-3224
_v7
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aChapter 1: The extracellular matrix goes - omics: resources and tools -- Chapter 2:The matrisome of model organisms: from in-silico prediction to big-data annotation -- Chapter 3: Detecting changes to the extracellular matrix in liver diseases -- Chapter 4: Characterization of Proteoglycanomes by Mass Spectrometry -- Chapter 5: Historical overview of integrated GAG-omics and proteomics -- Chapter 6: Extracellular matrix networks: from connections to functions -- Chapter 7: Integration of Matrisome Omics: Towards System Biology of the Tumor Matrisome -- Chapter 8: Proteomic and degradomic analysis of body fluids: applications, challenges and considerations -- Chapter 9: Regulation of Cell-Matrix Adhesion Networks: Insights from Proteomics -- Chapter 10: Integrative models for TGF- signaling and extracellular matrix.
520 3 _aThis book covers different omics aspects related to the extracellular matrix (ECM), namely specific omics resources focused on the extracellular matrix (e.g., databases, repositories and atlases), quantitative proteomics applied to specific extracellular matrices (e.g. basement membranes), biological processes such as ECM degradation (degradomics), cell-matrix interactions (adhesomes), signaling pathways, biomarker discovery and diseases, and interactomics (extracellular matrix interaction networks including not only protein-protein but also protein-glycosaminoglycan interactions). The volume also includes recent advances in glycomics and glycobioinformatics applied to proteoglycans and glycosaminoglycans, which are key biological players. The use of omics data to build dynamic models of ECM-regulated biological pathways is addressed, together with the requirement to standardize omic data, which is a prerequisite for the FAIR (Findability, Accessibility, Interoperability, and Reusability) guiding principles for scientific data management. This book will be of great interest to a broad readership from beginners to advanced researchers, who are interested in extracellular matrix omics and will inspire future research topics.
988 _aSpringer_BiomedLife_dic2020
650 7 _2embne
_aBioinformática
_9160489
650 7 _2embne
_aTejidos (Biología)
_9668849
700 1 _aRicard-Blum, Sylvie
_eeditor literario
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030583293
776 0 8 _iPrinted edition:
_z9783030583316
776 0 8 _iPrinted edition:
_z9783030583323
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-58330-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2021
_dz
_ea
_zSI