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999			_c329577 _d329577 _x1
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003			ES-MaUEC
005			20230102114424.0
008			201205s2020 gw | s |||| 0|eng d
020			_a9783030518561
024	7		_a10.1007/978-3-030-51856-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH324 _b2020 EB
245	0	0	_aAnimal Models for Endometriosis : _bevolution, utility and clinical relevance _cedited by Kathy L. Sharpe-Timms
250			_aFirst edition 2020
264		1	_aCham _bSpringer International Publishing _bImprint: Springer _c2020
300			_a1 recurso en línea (VII, 111 p 12 ilustraciones, 8 ilustraciones in color.
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Anatomy Embryology and Cell Biology _x0301-5556 _v232
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_aChapter 1. Introduction -- Chapter 2. Baboon model -- Chapter 3. Mechanisms of endometriosis-associated subfertility and novel therapeutic approaches discovered using a rat model -- Chapter 4. Animal models for pain or inflammation in endometriosis -- Chapter 5 Environmental endocrine disruptors and risk of endometriosis in mouse models.-Chapter 6. Deciphering the role of miRNAs in endometriosis pathophysiology using experimental endometriosis mouse models -- Chapter 7.Summation and future needs. .
520	3		_aThis new volume of our successful book series Advances in Anatomy, Embryology and Cell Biology focuses on the need for and use of animal models when studying endometriosis. Covering models ranging from rodents to baboons, it explores novel mechanisms involved in the pathophysiology of endometriosis. Topics range from the role of miRNAs and environmental endocrine disrupters to pain and endometriosis-associated subfertility. Estimated to affect up to 10% of women, endometriosis is a widespread and in some cases debilitating disease. While studies on the pathophysiology of the disease and the development of treatments for endometriosis-associated subfertility are called for, acquiring appropriate tissues from women with and without endometriosis in combination with physiologically relevant in vitro and in vivo laboratory models is an essential aspect. However, control subjects with similar ages, living environments and medical histories, besides endometriosis, are hard to find and attaining suitable human reproductive tissues is linked to an ongoing ethical discussion, especially when studying embryos. Laboratory models like rodent and monkey models are therefore needed to fill the research gap and support hypothesis-driven, randomized, controlled experimental design studies. In this book we highlight the latest developments and findings in endometriosis research using animal models. The book was written for scientists, physicians and medical students working in the field of reproductive science, and for women with endometriosis.
988			_aSpringer_BiomedLife_dic2020
650		7	_2embne _9671868 _aBiología _xInvestigación
650		7	_2embne _9405574 _aEndometriosis
700	1		_aSharpe-Timms, Kathy L _eeditor literario _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink
773	0		_tSpringer Nature eBook
776	0	8	_iPrinted edition: _z9783030518554
776	0	8	_iPrinted edition: _z9783030518578
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-51856-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2021 _dz _ea _zSI