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008 201127s2020 gw |a o |||| 0|eng d
020 _a9783030553593
024 7 _a10.1007/978-3-030-55359-3
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aR856
_b2020 EB
245 0 0 _aRegenerative Medicine and Stem Cell Biology
_cedited by Nagwa El-Badri
250 _aFirst edition 2020
264 1 _aCham
_bSpringer International Publishing
_c2020
300 _a1 recurso en línea (X, 374 páginas)
_b45 ilustraciones, 16 ilustraciones en color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aLearning Materials in Biosciences
_x2509-6125
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _aChapter 1. Basic Concepts of Stem Cells: The Facts and Hype in Stem Cells Research and Development -- Chapter 2. Embryonic and Pluripotent Stem Cells -- Chapter 3. Adult Stem Cells: Hematopoietic Stem Cells, and Control Of Hematopoiesis -- Chapter 4. Adult Stem Cells: Adult Stem Cells: Mesenchymal Stromal Cells, Endothelial Progenitor Cells and Pericytes -- Chapter 5. Cancer Stem Cells and the Development of Cancer -- Chapter 6. Stem Cell Applications In Metabolic Disorders: Diabetes Mellitus -- Chapter 7. Epigenetics in Stem Cell Biology -- Chapter 8. Practicum: Isolation of Bone Marrow and Adipose Tissue Mesenchyme Stromal Cells -- Chapter 9. Induced Pluripotent Stem Cells: Biology, History and in-vitro Generation -- Chapter 10. Tissue Engineering Modalities and Nanotechnology -- Chapter 11. Practicum: Scaffold engineering using the amniotic membrane -- Chapter 12. The Scientific Method, Ethical Consideration and Implications in Stem Cell Research.
520 3 _aThis textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.
988 _aSpringer_BiomedLife_dic2020
650 7 _2embne
_9143820
_aIngeniería biomédica
700 1 _aEl-Badri, Nagwa
_eeditor literario
_4http://id.loc.gov/vocabulary/relators/edt
_9677190
710 2 _aSpringerLink
773 0 _tSpringer Nature eBook
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-55359-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b02/2021
_dz
_eb
_zSI