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001			329544
003			ES-MaUEC
005			20230102114421.0
008			201126s2020 gw |a o |||| 0|eng d
020			_a9783030527808
024	7		_a10.1007/978-3-030-52780-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP34.5 _b2020 EB
245	0	0	_aBasic Epithelial Ion Transport Principles and Function : _bIon Channels and Transporters of Epithelia in Health and Disease _pVol. 1 _cedited by Kirk L. Hamilton, Daniel C. Devor
250			_aSecond edition 2020
264		1	_aCham _bSpringer International Publishing _c2020
300			_a1 recurso en línea (XIX, 563 páginas) _b106 ilustraciones, 71 ilustraciones en color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aPhysiology in Health and Disease _x2625-252X
490	0		_aBiomedical and Life Sciences (SpringerNature-11642)
490	0		_aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505	0		_a1. Techniques in Epithelial Transport -- 2. Understanding Transepithelial Current Measurements -- 3. Mathematical Modeling of Epithelial Ion Transport -- 4. Rationale of Epithelia Transport -- 5. Establishment of Epithelial Polarity -- 6. Molecular Mechanisms of Apical and Basolateral Sorting in Polarized Epithelial Cells -- 7. Membrane Protein Folding and Structure -- 8. Epithelial Ion Channel Folding and ER Associated Degradation (ERAD) -- 9. Fundamentals of Epithelial Cl- Transport -- 10. Fundamentals of Epithelial Na+ Absorption -- 11. Physiologic Influences of Transepithelial K+ Secretion -- 12. Volume Regulation in Epithelia -- 13. Fundamentals of Bicarbonate Secretion in Epithelia -- 14. Sexual Dimorphism of Epithelial Ion Channels -- 15. Non-coding RNA-Dependent Regulation of Channels/Transporters. .
520	3		_aThis book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.
988			_aSpringer_BiomedLife_dic2020
650		7	_2embne _aFisiología humana _9140024
650		7	_2embne _9144712 _aFisiopatología
700	1		_aHamilton, Kirk L., _eeditor literario _4http://id.loc.gov/vocabulary/relators/edt _996654 _d1953-
700	1		_aDevor, Daniel C., _eeditor literario _4http://id.loc.gov/vocabulary/relators/edt _996655 _d1961-
710	2		_aSpringerLink
773	0		_tSpringer Nature eBook
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-52780-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b02/2021 _dz _eb _zSI