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020 _a9783030517090
024 7 _a10.1007/978-3-030-51709-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQR181
_b2020 EB
245 0 0 _aLiver Immunology :
_bPrinciples and Practice
_cedited by M. Eric Gershwin, John M. Vierling, Atsushi Tanaka, Michael P. Manns.
250 _aThird edition
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2020.
300 _a1 recurso en línea (XV, 633 páginas)
_b145 ilustraciones, 135 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (SpringerNature-11642)
490 0 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
505 0 _a1. Core Concepts in Immunology: The Definition of Autoimmunity and Its Unique Application to the Seat of Tolerance, the Liver -- 2. The Liver as a Lymphoid Organ -- 3. The Uniqueness of Innate Immunity -- 4. Adaptive Immunity and the Clinical Definition of Autoantibodies.-5. Genetics of Autoimmune Liver Diseases -- 6. The Epigenetic Basis of Loss of Tolerance -- 7. Bile Acids and Bilirubin in Liver Immunology -- 8. The Microbiota-Gut-Liver Axis - Implications for the Pathophysiology of Liver Disease -- 9. Diagnostic Liver Immunology -- 10. The Pathologist's Approach to Reviewing Liver Histology -- 11. Geoepidemiology of Autoimmune Liver Diseases -- 12. Immune Responses to Bacterial Infections -- 13. Immunity of Parasitic Infections of the Liver -- 14. The Treatment of Bacterial and Parasitic Diseases of the Liver -- 15. Hepatitis A and Other Viral Infections -- 16. Hepatitis B Virus -- 17. Hepatitis C -- 18. Hepatitis D -- 19. Hepatitis E -- 20. Alcohol-Associated Liver Disease -- 21. Non-alcoholic Fatty Liver Disease: A Chapter in Liver Immunology -- 22. Primary Biliary Cholangitis -- 23. PSC - AIH Overlap -- 24. Primary Biliary Cholangitis: Autoimmune Hepatitis Overlap Syndrome -- 25. Primary Sclerosing Cholangitis -- 26. Autoimmune Hepatitis -- 27. IgG4-related Disease: Current Concept, Diagnosis, and Pathogenesis -- 28. Pediatric Liver Disease -- 29. Mechanisms of Acute Liver Failure -- 30. Immune-Mediated Drug-Induced Liver Injury -- 31. Hepatobiliary Cancers and Immunology -- 32. Acute-on-Chronic Liver Failure -- 33. The Pathogenesis of Liver Diseases in Pregnancy -- 34. Graft-Versus-Host Disease -- 35. Immunopathogenesis of Liver Cirrhosis -- 36. Immune-Mediated Liver Disease in the Transplanted Liver.
520 3 _aThe third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver's role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation. The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs. A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students. .
988 _aSpringer_BiomedLife_dic2020
650 7 _aInmunología
_2embne
_9138330
650 7 _aHígado
_xEnfermedades
_2embne
_9169917
700 1 _aGershwin, M. Eric
_eeditor
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aM. Vierling, John
_eeditor
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aTanaka, Atsushi
_eeditor
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aP. Manns, Michael
_eeditor
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030517083
776 0 8 _iPrinted edition:
_z9783030517106
776 0 8 _iPrinted edition:
_z9783030517113
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-51709-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b01/2021
_dz
_eo
_zSI