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008			200824s2020 si | s |||| 0|eng d
020			_a9789811568916
024	7		_a10.1007/978-981-15-6891-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC280.C6 _b2020 EB
245	0	0	_aLynch Syndrome : _bMolecular Mechanism and Current Clinical Practice _cedited by Naohiro Tomita
250			_aFirst edition 2020
264		1	_aSingapore _bSpringer International Publishing _c2020
300			_a1 recurso en línea (IX, 143 páginas) _b27 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_aarchivo de texto _bPDF
490	0		_aMedicine (SpringerNature-11650)
490	0		_aMedicine (R0) (SpringerNature-43714)
505	0		_a1 Molecular mechanism of Lynch syndrome -- 2 Clinical features of Lynch syndrome -- 3 Pathology of Lynch syndrome-associated tumors -- 4 Immunohistochemistry for mismatch repair proteins -- 5 Genetic analysis for Lynch syndrome -- 6 Lynch syndrome-associated gynecological malignancies -- 7 Lynch syndrome-associated urological malignancies -- 8 Screening for Lynch syndrome -- 9 Surveillance Colonoscopy for Lynch Syndrome Patients -- 10 Surgical approach for colorectal cancer in patients with Lynch syndrome -- 11 Immunotherapy for Lynch syndrome patients -- 12 Chemoprevention for Lynch syndrome-associated malignancies -- 13 International collaboration for Lynch syndrome.
520	3		_aThis book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition. Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analysis, the standard treatment strategy for patients and family members of LS have been steadily improving. In this book, experts describe the disease's manifestations, discuss state-of-the-art diagnosis and management options, and offer a cutting-edge overview of the genetic and epigenetic basis of the syndrome. Providing essential insights into this new phase in the management of LS, this book is a valuable resource not only for colorectal surgeons, but also for general gastrointestinal clinicians, gynecologists, oncologists and all basic researchers with an interest in LS.
988			_aSpringer_Medicine_2020
650		7	_2embne _9182269 _aColon _xCáncer
650		7	_2embne _9182442 _aRecto _xCáncer
650		7	_2embne _9140427 _aEnfermedades hereditarias
700	1		_aTomita, Naohiro _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811568909
776	0	8	_iPrinted edition: _z9789811568923
776	0	8	_iPrinted edition: _z9789811568930
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-15-6891-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _b12/2020 _ea _zSI