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020 _a9783030523558
024 7 _a10.1007/978-3-030-52355-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aTK7868.L6
_b2020 EB
100 1 _aBaig, Hasan
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_9676912
245 1 0 _aGenetic Design Automation :
_bA Practical Approach for the Analysis, Verification and Synthesis of Genetic Logic Circuits
_cby Hasan Baig, Jan Madsen
250 _aFirst edition 2020
264 1 _aCham
_bSpringer International Publishing
_c2020
300 _a1 recurso en línea (XVI, 164 páginas)
_b158 ilustraciones, 148 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _aarchivo de texto
_bPDF
490 0 _aEngineering (SpringerNature-11647)
490 0 _aEngineering (R0) (SpringerNature-43712)
505 0 _aIntroduction -- Fundamentals of Molecular Biology and Genetic Circuits -- Dynamic Virtual Analyzer and Simulator -- Genetic Circuits Timing Analysis -- Genetic Circuits Logic Analysis -- Technology Mapping of Genetic Circuits -- Parameter Estimation and Sensitivity Analysis -- Learn to program rapidly with graphical programming -- Project 1 - Stochastic Simulation -- Project 2 - Parsing SBML -- Project 3 - Circuit generation with SBOL.
520 3 _aThis textbook introduces readers to the recent advances in the emerging field of genetic design automation (GDA). Starting with an introduction and the basic concepts of molecular biology, the authors provide an overview of various genetic design automation tools. The authors then present the DVASim tool (Dynamic Virtual Analyzer and Simulator) which is used for the analysis and verification of genetic logic circuits. This includes methods and algorithms for the timing and threshold value analyses of genetic logic circuits. Next, the book presents the GeneTech tool (A technology mapping tool for genetic circuits) and the methods developed for optimization, synthesis, and technology mapping of genetic circuits. Chapters are followed by exercises which give readers hands-on practice with the tools presented. The concepts and algorithms are thoroughly described, enabling readers to improve the tools or use them as a starting point to develop new tools. Both DVASim and GeneTech are available from the developer's website, free of charge. This book is intended for a multidisciplinary audience of computer scientists, engineers and biologists. It provides enough background knowledge for computer scientists and engineers, who usually do not have any background in biology but are interested to get involved in this domain. This book not only presents an accessible basic introduction to molecular biology, it also includes software tools which allow users to perform laboratory experiments in a virtual in-silico environment. This helps newbies to get a quick start in understanding and developing genetic design automation tools. The third part of this book is particular useful for biologists who usually find it difficult to grasp programming and are reluctant to developing computer software. They are introduced to the graphical programming language, LabVIEW, from which they can start developing computer programs rapidly. Readers are further provided with small projects which will help them to start developing GDA tools.
988 _aSpringer_Engineering_2020
650 7 _2embne
_aCircuitos lógicos
_9139135
650 7 _2embne
_aIngeniería genética
_9141520
650 7 _2embne
_9143820
_aIngeniería biomédica
700 _aMadsen, Jan.
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_997436
773 0 _tSpringer Nature eBook
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-52355-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _dz
_b01/2021
_eb
_zSI