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| 003 | ES-MaUEC | ||
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| 007 | cr nn nnnaamaa | ||
| 008 | 200926s2020 gw | s |||| 0|eng d | ||
| 020 | _a9783030534332 | ||
| 024 | 7 |
_a10.1007/978-3-030-53433-2 _2doi |
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_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC |
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| 050 | 4 |
_aQP551 _b2020 EB |
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| 100 | 1 |
_aHossain, Mahmud _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9676871 |
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| 245 | 1 | 0 |
_aSelected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics : _bA Comprehensive View _cMahmud Hossain |
| 250 | _aFirst edition | ||
| 264 | 1 |
_aCham _bSpringer International Publishing : _bImprint: Springer _c2020 |
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| 300 |
_a1 recurso en línea (XVII, 283 páginas) : _b102 ilustraciones, 86 ilustraciones a color |
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| 336 |
_2rdacontent _aTexto _btxt |
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| 337 |
_2rdamedia _aelectrónico _bc |
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| 338 |
_2rdacarrier _arecurso electrónico _bcr |
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| 347 |
_aArchivo de texto _bPDF |
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| 490 | 0 | _aBiomedical and Life Sciences (SpringerNature-11642) | |
| 490 | 0 | _aBiomedical and Life Sciences (SpringerNature-43708) | |
| 505 | 0 | _aChapter 1: Introduction -- Chapter 2: The mass spectrometer and its components -- Chapter 3: Selected reaction monitoring mass spectrometry (SRM-MS) -- Chapter 4: Development of SRM-MS experiment -- Chapter 5: Bioinformatics tools for SRM-MS -- Chapter 6: Quantification by SRM-MS -- Chapter 7: SRM-MS applications in proteomics -- Chapter 8: SRM-MS for posttranslational modification (PTM) analysis -- Chapter 9: Challenges, current trends and future directions -- Bibliography -- Index. | |
| 520 | 3 | _aCovering a wide-ranging facet of a "gold-standard" targeted mass spectrometry (MS) method for the consistent detection and accurate quantification of preselected proteins in complex biological matrices, Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics: A Comprehensive View describes: The knowledge-based development of highly efficient SRM methodology including assay workflow, selection of proteins, peptides, transitions and its validation, and quality assessment Available bioinformatic tools - for both pre-acquisition method development and post-MS acquisition data analysis and data repositories Various relative and absolute quantification techniques SRM-MS' widespread applications in biomarker development and in clinical studies, as well as in the analysis of various posttranslational modifications (PTMs) Current challenges and contemporary trends to overcome those difficulties In addition, it features the historical development of modern-day mass spectrometry with its vivid applications and also covers basic MS instrumentation, ionization techniques, and various proteomics approaches. Comprehensive discussion, extensive references at the end of each chapter, and the list of review articles in the bibliography offer invaluable resources for advanced readings. Researchers from the undergraduate to postgraduate level and beyond in both academic or industry settings studying and working on mass spectrometry and/or proteomics will benefit from this book. | |
| 988 | _aSpringer_BiomedLife_13102020 | ||
| 650 | 7 |
_aProteómica _2embne _9430647 |
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| 650 | 7 |
_aEspectroscopia _2embne _9140515 |
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| 650 | 7 |
_aEspectrometría de masas _2embne _9141447 |
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_iPrinted edition: _z9783030534325 |
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_iPrinted edition: _z9783030534349 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783030534356 |
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-53433-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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_b01/2021 _dz _eo _zSI |
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